sage of Ultrasound to measure Chest muscle thickness for predicting successful weaning in patients on Mechanical ventilation in the Intensive care unit

Not Applicable

Conditions: Health Condition 1: R652- Severe sepsis

Registration Number: CTRI/2024/04/066209

Lead Sponsor: VARDHMAN MAHAVIR MEDICAL COLLEGE AND SAFDARJUNG HOSPITA

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

On mechanical ventilation for a minimum period of 24 hours with readiness of weaning as assessed by:

1)recovery from the cause of respiratory failure

2)stable hemodynamic status with no requirement for vasopressors

3)fully conscious with GCS more than or equal to 14

4)Fraction of inspired oxygen(FiO2)less then 0.5,Positive end expiratory pressure(PEEP)less than or equal to 5cm H20,Respiratory rate less than 30,Partial pressure of oxygen(Pao2)/Fraction of inspired oxygen(FiO2) more than 200

Exclusion Criteria

1.Pneumothorax, pleural effusion, collapse, fibrosis

2.Rib fracture, thoracic surgery, thoracotomy

3.History of neuromuscular disease, diaphragmatic palsy, mechanical factor or surgical dressing over the chest.

4.Tracheostomy tube in situ

5.Pregnancy, ascites, morbid obesity

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the sensitivity and specificity of ultrasonographic guided parasternal intercostal muscle thickness fraction (PICTF%) for predicting weaning outcome in patients on mechanical <br/ ><br>ventilation in the intensive care unit. <br/ ><br>Timepoint: After 10 mins of Starting Spontaneous breathing trail (SBT)for weaning the patient from mechanical ventilation <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
To compare the predictive values of diaphragmatic thickness fraction (DTF) and parasternal intercostal muscle thickness fraction (PICTF) on ultrasonography for predicting weaning outcome in patients on mechanical ventilation in the intensive care unit.Timepoint: After 10 mins of Starting Spontaneous breathing trail (SBT)for weaning the patient from mechanical ventilation <br/ ><br>