Chest muscle function in patients during removal from ventilator in IC

Not Applicable

• Conditions: Health Condition 1: J962- Acute and chronic respiratory failure

• Registration Number: CTRI/2022/03/040965
• Lead Sponsor: Souvik Chaudhuri

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients who were mechanically ventilated in ICU

and meet the following criteria will be put on SBT for weaning will be included.

Following will be the criteria to consider for weaning in the ICU which is used by any

intensivist at our institute:

1. Fraction of inspired oxygen (FiO2 < 0.5)

2. Positive end expiratory pressure (PEEP) <= 5cmH2O

3. Partial pressure of oxygen in arterial blood (PaO2)/FiO2 > 150 mmHg

4. Respiratory rate < 35/minute

5. Tidal volume >5mL /kg,

6. Minute ventilation < 10L/min

7. No abnormality in electrolyte parameters, absence of hemodynamic instability, resolution

of the initial cause of ventilator requirement and patients awake with the ability to cough.

Exclusion Criteria

1. Patients with chest wall abnormalities,

2. Distorted chest wall anatomy,

3. Patients with any known neuromuscular weakness, 4. Patients with any known diaphragmatic disorders

5. Pregnant patients,

6. Patients with known cardiac dysfunction on initial ECHO during hospital admission

7. Any patient in whom the SBT is aborted even before 30 minutes duration as deemed by the intensivist will be excluded.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Successful weaning from ventilatorTimepoint: 48 hours after removal of ventilator

Secondary Outcome Measures

Name	Time	Method
Survival of ICU stayTimepoint: 28 days from day of admission to IC