NCT01635049已完成不适用
Correlating Time-Lapse Parameters Detected by the Eeva™ System With Comprehensive Chromosome Screening Results,Implantation and Live Birth
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 试验地点
- 2
- 主要终点
- Eeva time-lapse parameters and CCS
研究概览
简要总结
The purpose of this research study protocol is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) and correlate Eeva System parameters with comprehensive chromosome screening (CCS) results, implantation and live birth.
详细描述
The present study was designed to determine if there is a correlation between the Eeva System parameters and CCS results. Embryos will be selected for transfer based on CCS results and morphology. The Clinical site will have no access to the Eeva analysis at the time of the transfer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 43 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Subject is ≤43 years of age.
- •Women undergoing fresh IVF treatment using her own eggs or donor eggs and undergoing CCS, as recommended based on medical need by the clinical site reproductive endocrinologist.
- •Fertilization using only ejaculated sperm (fresh or frozen) - no surgically retrieved sperm.
- •Willing to have all 2PN embryos monitored by Eeva
- •Not previously enrolled in this study.
- •No concurrent participation in another clinical study.
- •Willing to comply with study protocol and procedures and able to speak English.
- •Willing to provide written informed consent.
排除标准
- •Prior IVF cycle with < 4 x 2PN
- •Diminished ovarian reserve as demonstrated by any one of the following:
- •BAFC < 6 at time of cycle start
- •Maximum prior FSH > 15
- •AMH < 0.5
结局指标
主要结局
Eeva time-lapse parameters and CCS
时间窗: 5-6 days
Analyse the correlation of time-lapse parameters collected by the Eeva System and comprehensive chromosome screening (CCS) results.
次要结局
- Correlation of time-lapse parameters collected by the Eeva System and implantation rate.(6 weeks)
- Correlation of time-lapse parameters collected by the Eeva System and clinical pregnancy rate(6 weeks)
- Correlation of time-lapse parameters collected by the Eeva System and ongoing pregnancy rate(7 - 8 weeks)
- Correlation of time-lapse parameters collected by the Eeva System and delivery rate(live birth)
- Correlation of time-lapse parameters collected by the Eeva System and spontaneous miscarriage rate(live birth)
- Correlation of time-lapse parameters collected by the Eeva System and multiple pregnancy rate(live birth)
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
不适用
Correlating Time-Lapse Parameters With aCGH Testing in IVF Treatment (aCGH Study)InfertilityNCT02141685Progyny, Inc.50
终止
4 期
Time-lapse Evaluation of Embryo Development After Stimulation With One of Two Different Gonadotrophins.Patients for In Vitro Fertilization(IVF)TreatmentNCT01345812University of Aarhus291
Enrolling By Invitation
不适用
Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation SequencingInfertility, FemaleInfertility, MaleInfertilityAneuploidyIVFNCT06419127Gattaca Genomics2,000
已完成
不适用
Use of Time-lapse Morphological Kinetics in the Selection of BlastocystsViabilityNCT02081859The Cleveland Clinic300
Unknown
不适用
A Study Select Top-grade Embryo by Time-lapse ImagingTop-grade EmbryoNCT02965222Shanghai First Maternity and Infant Hospital150