Does Use of Time-lapse Morphological Kinetics in the Selection of Blastocysts for Transfer Improve Pregnancy Rates?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 2
- 主要终点
- Clinical Pregnancy Rate
研究概览
简要总结
This is a randomized controlled observational trial to determine if data obtained from the embryoscope is helpful in determining which blastocysts to transfer.
详细描述
Materials and Methods:
Patient Selection:
Patients undergoing an IVF cycle at the Cleveland Clinic Reproductive Endocrinology and Infertility clinic with the plan for transfer of embryo(s) will be offered the opportunity to participate in this study. We would like a total enrollment 300 patients with 150 in each group. The only patients excluded will be those undergoing pre-implantation genetic testing and/or chromosome screening.
Study Design This will be a prospective randomized controlled trial where all patients who agree to participate will be randomized to having embryo selection for transfer based solely on conventional criteria or alternatively conventional criteria in conjunction with morphokinetic criteria.
Enrollment:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing an IVF cycle between the age of 18-45 at the Cleveland Clinic Reproductive Endocrinology and Infertility clinic with the plan for transfer of embryo(s) will be offered the opportunity to participate in this study.
排除标准
- •The only patients excluded will be those undergoing pre-implantation genetic testing and/or chromosome screening.
结局指标
主要结局
Clinical Pregnancy Rate
时间窗: 6 weeks
Patients will have a ultrasound to document fetal heart rate approximately 6 weeks after start of IVF cycle.
次要结局
- Implantation Rate(6 weeks)