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临床试验/NCT01692951
NCT01692951已完成不适用

Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer

The Cleveland Clinic1 个研究点 分布在 1 个国家目标入组 220 人开始时间: 2012年8月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
220
试验地点
1
主要终点
Compare Concentration of Fatty Acids and Their Metabolites

研究概览

简要总结

This study aims to evaluate the performance of serum free fatty acids as biomarkers for the identification of lung cancer.

详细描述

We will compare the concentration of free fatty acids and their metabolites between patients with lung cancer and control pulmonary patients without known cancer. The diagnostic accuracy will be assessed for potential predictors.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
40 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age from 40 to 80
  • Lung adenocarcinoma with pathological diagnosis
  • Lung squamous cell carcinoma with pathological diagnosis
  • Control patients should have at least one of the following criteria: (1) current or ex-smoker with at least a 10 pack-year history, (2) a first-degree relative with a history of lung cancer, or (3) a clinical diagnosis of COPD.

排除标准

  • Lung cancer patient without serum sample before the initiation of treatment

结局指标

主要结局

Compare Concentration of Fatty Acids and Their Metabolites

时间窗: At the time of diagnosis, prior to the initiation of lung cancer treatment

Biochemical analysis of serum sample was conducted by an investigator who was strictly blinded to cancer status and patient characteristics.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

d sessler

MD

Outcomes Research Consortium

研究点 (1)

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