Effect and timing of early traditional Chinese medicine intervention in severe acute pancreatitis
- Conditions
- severe acute pancreatitis
- Registration Number
- ITMCTR2200005908
- Lead Sponsor
- Jinhua Municipal Central Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) Meet the diagnostic criteria of AP;
(2) Meet the diagnostic criteria of Fu excess heat syndrome;
(3) Meet the diagnostic criteria of predicted SAP: ? APACHE II score = 8, and/ or ? BISAP score = 3, and/ or ? Pass score > 140, and/ or ? CRP>150mg/mL.
(4) Admission within 48 hours after onset (onset of abdominal pain);
(5) Regardless of gender, 18-85 years old;
(6) Agree to participate in this study and obtain the written informed consent of the patient or his legal representative.
(1) Patients with chronic pancreatitis, pancreatic tumors, or chronic serious diseases of other organ systems, as well as malignant tumors;
(2) Patients with gastrointestinal perforation, gastrointestinal bleeding and complete intestinal obstruction;
(3) Patients with serious condition who need non medical treatment such as surgery and peritoneal lavage;
(4) Patients with a history of trauma and surgery before onset;
(5) Patients who joined other clinical trials 3 months before onset;
(6) Pregnancy complicated with acute pancreatitis or lactation;
(7) Patients who were treated with traditional Chinese medicine before admission.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of organ failure;Incidence of SIRS;
- Secondary Outcome Measures
Name Time Method ength of stay;Symptom relief;Inflammatory index;