Intubating Conditions at Various Levels of Neuromuscular Blockade
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 170
- 试验地点
- 2
- 主要终点
- Number of Subjects With Optimal Intubating Conditions
研究概览
简要总结
The purpose of this research is to learn about the difference in the endotracheal intubation condition (ease of using a device to view vocal cords, position of vocal cords, and patient's reaction to endotracheal tube insertion) and determining the appropriate time to perform the intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients willing to participate and provide an informed consent.
- •Patients undergoing elective surgical procedures that require use of NMBA agents (rocuronium) administered intraoperatively.
排除标准
- •Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
- •Patients with systemic neuromuscular diseases such as myasthenia gravis.
- •Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents; i.e., severe renal impairment or end-stage liver disease.
- •Patients having surgery that would involve prepping the arm into the sterile field.
- •Patients receiving a rapid sequence induction.
结局指标
主要结局
Number of Subjects With Optimal Intubating Conditions
时间窗: Approximately 15 minutes after intubation
The number of subjects who had optimal intubating conditions (total composite score of 3) will be evaluated by the healthcare providers using a scale that includes 3 variables (ease of laryngoscopy, vocal cord position, and reaction to tracheal tube insertion) with 3 response options per each evaluation. The composite score (1-3) will be used, with the lowest total score of 3 correlating with optimal intubating conditions and the highest score of 9 representing the worse possible intubating conditions.
次要结局
未报告次要终点
研究者
J. Ross Renew, M.D.
Principal Investigator
Mayo Clinic