To compare between two groups of patients suffering from chronic lung disease who fails to maintain breathing on artificial machine through mask , the two groups includes one who receives oral tablets and the other who receives injections
Phase 2
- Conditions
- Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
- Registration Number
- CTRI/2024/07/069844
- Lead Sponsor
- Jawarhalal Instiute of Postgraduate Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
?COPD in moderate to severe acute exacerbation requiring NIV admitted in RICU
?Age more than 40 years
?Informed Consent for study
Exclusion Criteria
Contraindications of NIV:
1. Unable to tolerate NIV reduced consciousness and inability to protect the airways
2. Uncooperative patient
3. Copious respiratory secretions
4. Nausea with vomiting
5. Facial trauma burns
6. Shock patients requiring inotropes
Contraindications of steroids:
1. H/o git bleed in the past 1 month
Others:
1. Chronic kidney injury
2. Left heart failure
3. Cor pulmonale in failure
4. liver failure
5. pneumonia
6. pneumothorax requiring intervention
7. pregnancy
8. lactating mother
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method