Skip to main content
Clinical Trials/CTRI/2024/07/069844
CTRI/2024/07/069844
Not Yet Recruiting
Phase 2

Comparing non-invasive ventilation failure with oral versus intravenous systemic steroids in the treatment of moderate to severe exacerbation of chronic obstructive pulmonary disease patients in the respiratory intensive care unit: Pilot study - NI

Jawarhalal Instiute of Postgraduate Medical Education and Research0 sites0 target enrollmentTBD

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
Jawarhalal Instiute of Postgraduate Medical Education and Research
Status
Not Yet Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Interventional

Investigators

Sponsor
Jawarhalal Instiute of Postgraduate Medical Education and Research

Eligibility Criteria

Inclusion Criteria

  • ?COPD in moderate to severe acute exacerbation requiring NIV admitted in RICU
  • ?Age more than 40 years
  • ?Informed Consent for study

Exclusion Criteria

  • Contraindications of NIV:
  • 1\. Unable to tolerate NIV reduced consciousness and inability to protect the airways
  • 2\. Uncooperative patient
  • 3\. Copious respiratory secretions
  • 4\. Nausea with vomiting
  • 5\. Facial trauma burns
  • 6\. Shock patients requiring inotropes
  • Contraindications of steroids:
  • 1\. H/o git bleed in the past 1 month
  • 1\. Chronic kidney injury

Outcomes

Primary Outcomes

Not specified

Similar Trials

Not Yet Recruiting
N/A
Predicting Failure Of Ventilation In Breathless PatientsHealth Condition 1: null- Type 2 Respiratory Failure
CTRI/2017/02/007817I60
Not Yet Recruiting
N/A
A Clinical Study to find out if a Scoring System can be used to predict whether a patient needs to be placed on an Invasive Ventilator.Health Condition 1: N179- Acute kidney failure, unspecifiedHealth Condition 2: I509- Heart failure, unspecifiedHealth Condition 3: J189- Pneumonia, unspecified organismHealth Condition 4: J989- Respiratory disorder, unspecifiedHealth Condition 5: J22- Unspecified acute lower respiratory infection
CTRI/2024/01/061143Sri Ramachandra Institute of Higher Education and Research
Completed
Phase 4
Efficacy of non-invasive ventilation versus standard oxygen therapy in emergency patients with respiratory distress: A randomized controlled trialrespiratory distress&#44emergency departmentrespiratory distressnon&#45invasive ventilationrespiratory rate
TCTR20150325002Faculty of medicine, Siriraj Hospital, Mahidol University114
Not Yet Recruiting
Phase 1
ess invasive surfactant administration vs Intubation, surfactant and extubation in preterm neonates with respiratory distress syndrome
CTRI/2021/04/032720Dr Ashu Jamwal
Not Yet Recruiting
Phase 4
To assess the use of lignocaine alone versus lignocaine and magnesium sulphate together in nebulizing patients with predicted difficult airway for awake fiberoptic- guided nasotracheal intubatioHealth Condition 1: O- Medical and SurgicalHealth Condition 2: J398- Other specified diseases of upperrespiratory tract
CTRI/2024/05/067158Vardhman Mahavir Medical College and Safdarjung Hospital