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Glutathione Status in Platelets From Patients With Type 2 Diabetes: Therapeutic Potential of N-acetylcysteine to Help Prevent Platelet Hyperaggregability - NAC study

Conditions
Platelet Aggregation in type 2 diabetes
Registration Number
EUCTR2008-001620-31-GB
Lead Sponsor
HS Highland
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
44
Inclusion Criteria

Men or post menopausal women with type 2 diabetes
Not recieving aspirin (group A)
Receiving Aspirin (Group B)

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Very poorly controlled diabetes (HbA1c > 10%)
Significant hypertriglyceridaemia (TG > 4 mmol/L)
Renal disease (creatinine > 150 umol/L)
Current or recently stopped smokers (< 6 months)
Patients receiving other anti platelet therapy (i.e. clopidogrel, dipyridamole), or lipid lowering therapy where the patients are unable or unwilling to stop therapy for the duration of study participation.
Patients with asthma
Current use of tetracycline antibiotics or cough suppressants

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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