Study on the clinical effect of Zhibai Fuxia decoction combined with rhGH on prediction of adult height in children with precocious puberty

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•(1) Those who met the diagnostic criteria of peripheral precocious puberty, had abnormal sex hormone, B-ultrasound and X-ray examination, but the sex hormone provocation test did not meet the diagnosis of true precocious puberty;
•(2) In addition to the main symptoms, it was accompanied by five heart trouble, hot flushes, fear of heat, red cheekbones, night sweats, irritability and irritability, dry throat and dry mouth, short yellow urine, dry stool, or no moss and thin pulse.
•(3) The age of onset was less than 8 years in girls and 9 years in boys;
•(4) Girls have not menarche, and their bone age is less than 11 years old or (bone age age age) < 2 years old; boys have no ejaculation and their bone age is less than 13 years old;
•(5) Those who sign informed consent.

•(1) True precocious puberty caused by intracranial organic lesions;
•(2) Pseudoprecocious puberty, including adrenal or ovarian tumors, fibrous dysplasia associated with precocious puberty syndrome, ingestion of Estrogen;
•(3) Precocious puberty of the opposite sex;
•(4) Tanner IV and with menses;
•(5) Previous history of mental illness or severe heart, brain or neurological disorder.

发起方

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine