A clinical study on the efficacy of Xuefu Zhuyu Decoction in acute radiation esophagitis in esophageal cancer radiotherapy
- Conditions
- esophagus cancer
- Registration Number
- ITMCTR2100004685
- Lead Sponsor
- Affiliated Hospital of Nanjing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1.Patients with limited stage squamous cell carcinoma of the oesophagus with clear pathological diagnosis and suitable for concurrent radiotherapy;
2.KPS score >= 60 and expected survival > 3 months; can eat a liquid diet;
3.Tolerate and agree to receive concurrent radiotherapy;
4.Peripheral leukocytes >= 4.0 x 10^9/L, haemoglobin >= 90g/L and platelets >= 80 x 10^9/L before radiotherapy; no oesophageal perforation or active bleeding; no serious cardiac, pulmonary, hepatic or renal dysfunction or coagulation dysfunction;
5.No other contraindications to radiotherapy;
6.Willing to join this clinical study and sign the informed consent form.
1.Those with advanced disease who are not suitable for simultaneous radiotherapy;
2.Poor compliance; Allergy to experimental drugs;
3.Concurrent participation in other clinical trials;
4.Other serious illnesses, such as the combination of other tumours or serious infections;
5.Those with mental illness or mental retardation who are unable to express symptoms accurately.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory factors;Indicators of radioactive esophagitis;Coagulation index;Radiosensitization index;
- Secondary Outcome Measures
Name Time Method Safety index;