Attenuation of haemodynamic response to tracheal intubation with oral gabapentin and midazolam in breast cancer patients
Completed
- Conditions
- SurgeryModified radical mastectomy under general anaesthesia
- Registration Number
- ISRCTN15943548
- Lead Sponsor
- ational Cancer Institute, Cairo University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
1. ASA1 or 2 patients
2. Between 18 to 65 years of age
3. Undergoing modified radical mastectomy under general anaesthesia
Exclusion Criteria
1. Allergy to gabapentin or midazolam
2. Severe renal or liver insufficiency
3. Patient refusal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Heart rate measured by electrocardiogram and pulse oximetry <br>2. Blood pressure measured by non invasive blood pressure monitor<br>Measured at baseline and at 0, 1, 3, 5, 10, 15 and 30 minutes of intubation
- Secondary Outcome Measures
Name Time Method 1. Sedation measured using Ramsay Sedation Scale<br>2. Side effects (e.g. nausea or vomiting) recorded by physician staff<br>Recorded over 24 h postoperatively