Role of Thymidine Phosphorylase(TP), Dihydropyrimidine Dehydrogenase(DPD)and Thymidylate synthase(TS)for Predicting the Prognosis and Therapeutic Effects of Doxifluridine, An Intermediate form of Capecitabine, in adjuvant therapy for postoperative Node positive colorectal cancer(DukesC); Findings from a multicenter Phase2 trial.
Phase 2
- Conditions
- Dukes'C colorectal cancer which is removed curatively and surgically
- Registration Number
- JPRN-C000000077
- Lead Sponsor
- Multicenter Clinical Study Group of Osaka
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
appendiceal carcinoma and anal canal carcinoma of anal gland origin Multiple cancer patients except m cancer apparent infection sever postoperative complications active peptic ulcer Cardiac infarction within three months-uncontrolled hypertension -diabetes mellitus, uncontrolled or controlled with insulin -unstable angina, myocardial infarction needed to treat or febrile neutropenia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disease-free survival
- Secondary Outcome Measures
Name Time Method Overall survival