Feasibility and pharmacokinetics of nebulized S-ketamine inhalation in healthy adults

Completed

• Conditions: pain; pharmacokinetics

• Registration Number: NL-OMON42367
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Subjects of either sex (10 men/10 women), aged 18-39 years with a body mass index <= 30 kg/m2

Exclusion Criteria

Severe medical disease including pulmonary disease, hypertension, liver/renal disease, neurological disorders, diaphragmatic hernia/pyrosis; (history of) psychiatric or neurological disease; pregnancy/lactation; allergy to study medication; (history of) illicit drug use/alcoholism; concurrent participation in another trial.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Safety<br /><br>Pharmacokinetics</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Pain relief</p><br>