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Feasibility and pharmacokinetics of nebulized S-ketamineinhalation in healthy adults the NebuKet study

Recruiting
Conditions
- ketamine<br />- nebulization<br />- pharmocokinetics<br />- analgesia<br />- side effects
Registration Number
NL-OMON23977
Lead Sponsor
anesthesiology department of LUMC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

men/women 18-39years BMI <30kg/m2

Exclusion Criteria

pulmonary disease, hypertensin, liver/renal disease, neurological disorders diaphragmatic hernia/pyrosis, (history of) psychiatric or neurological disease, pregnancy/lactation, allergy to study medication, (history of) illicit drug use/alcoholism; concurrent participation in another trial

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
safety of procedure
Secondary Outcome Measures
NameTimeMethod
analgesia, pharmakinetics ans hemodynamic effects (Blood pressure, cardiac output, heart rate
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