Effect of different flow rates of anaesthetic gas on pressure changes in the brain measured by changes in diameter of nerve behind the eye in patients undergoing elective laproscopic cholecystectomy under General anaesthesia
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2024/03/064663
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients posted for elective Laparoscopic cholecystectomy under General anesthesia
2. American Society of Anaesthesiologists (ASA) class I and II patients
Exclusion Criteria
1. Patients with acute or chronic eye disease,
2. Patients with history of drug abuse, acute alcohol intoxication, chronic alcohol use.
3. Patients with known history of neurological disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the changes Optic nerve sheath diameter using the fresh gas flow of 1.5 litres and 3 litresTimepoint: T1: in the supine position before anesthesia induction; <br/ ><br> <br/ ><br>T2:5 min after pneumoperitoneum; <br/ ><br> <br/ ><br>T3: 30 min after pneumoperitonium; <br/ ><br> <br/ ><br>T4: 15 min after extubation.
- Secondary Outcome Measures
Name Time Method To measure changes in hemodynamic parameters (HR,BP, MAP, SPO2, ETCO2) at different flow ratesTimepoint: T1: in the supine position before anesthesia induction; <br/ ><br> <br/ ><br>T2:5 min after pneumoperitoneum; <br/ ><br> <br/ ><br>T3: 30 min after pneumoperitonium; <br/ ><br> <br/ ><br>T4: 15 min after extubation.
Related Research Topics
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How do varying anaesthetic fresh gas flow rates influence intracranial pressure and optic nerve sheath diameter in laparoscopic cholecystectomy patients?
What is the comparative effectiveness of high vs. low fresh gas flow rates on ONSD changes in CTRI/2024/03/064663 laparoscopic cholecystectomy patients?
Are there predictive biomarkers for optic nerve sheath diameter variability in response to anaesthetic gas flow rates during laparoscopic cholecystectomy?
What adverse events are associated with altered anaesthetic gas flow rates affecting intracranial pressure in laparoscopic cholecystectomy patients?
How do alternative anaesthetic agents or techniques compare to standard gas flow rates in modulating optic nerve sheath diameter during laparoscopic cholecystectomy?