Comparing effect of different flow of anaesthesia and pneumoperitoneum on intracranial pressure by measuring optic nerve sheath diameter using ultrasound machine during laparoscopic cholecystectomy surgery.
Phase 4
- Conditions
- Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitisHealth Condition 2: K807- Calculus of gallbladder and bile duct without cholecystitisHealth Condition 3: K800- Calculus of gallbladder with acutecholecystitisHealth Condition 4: K801- Calculus of gallbladder with othercholecystitisHealth Condition 5: K802- Calculus of gallbladder without cholecystitisHealth Condition 6: K808- Other cholelithiasis
- Registration Number
- CTRI/2024/05/067818
- Lead Sponsor
- Dr Riya Rautela
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of either sex in the age group 18-65
years posted for elective surgery.
2. Belonging to ASA Grade I and II.
3. Patients willing to participate in the study.
Exclusion Criteria
1. Patient unwilling to participate in the study.
2. Pregnant female.
3. Previous eye surgery.
4. Head and neck surgery.
5. Previous orbital trauma or surgical history.
6. Intracranial space covering lesions with high
ICP.
7. Chronic kidney disease.
8. Cirrhosis with ascitis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the change in ONSD at 30 minutes after pneumoperitoneum among patients undergoing laparoscopic cholecystectomy with varying flow and varying intraabdominal pressure.Timepoint: 30 minutes after creation of pneumoperitoneum.
- Secondary Outcome Measures
Name Time Method 1.To assess the change in ONSD at post induction, 15 mins after pneumoperitoneum in supine position and 10 mins after desufflation. <br/ ><br>2.To assess the change in ONSD with low flow and normal flow anaesthesia. <br/ ><br>3.Correlation of post operative nausea vomiting and headache with change in ONSD. <br/ ><br>4.To assess the change of hemodynamics like MAP, HR with PP, and flow of anaesthesia. <br/ ><br>5.To assess the change of Peak airway pressure with PP and flow of anaesthesia. <br/ ><br>6.To assess the change of ETCO2 with PP and flow of anaesthesia.Timepoint: Immediately after induction, 15 mins after pneumoperitoneum in supine position and 10 mins after desufflation.