Comparison of the Efficacy of High-flow Nasal Oxygen Therapy and Facial Mask Ventilation on the Increase of the Oxygen Reserve Index During Anesthetic Induction

Not Applicable

Completed

• Conditions: Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia
• Interventions: Procedure: High-flow nasal oxygen technique; Procedure: Mask ventilation technique

• Registration Number: NCT04291339
• Lead Sponsor: Yonsei University

Brief Summary

The purpose of this study is to compare the ability of oxygenation with high-flow nasal oxygen therapy and mask ventilation technique for induction of anesthesia in adult patients who are planning to undergo surgery under general anesthesia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-02-28
• Study First Submitted QC: 2020-02-28
• Study First Posted: 2020-03-02
• Study Start: 2020-11-11
• Primary Completion: 2021-01-12
• Study Completion: 2021-01-12
• Status Verified: 2021-05
• Last Update Submitted: 2021-05-28
• Last Update Posted: 2021-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 198

Inclusion Criteria

• adult patients aged over 19 years who are scheduled for sleep endoscopy

Exclusion Criteria

• basal skull fracture
• facial anomaly
• consciousness disorder
• Risk of aspiration
• necessity of awake fiberoptic intubation due to the large vocal cord mass, endotracheal tumor or bleeding.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High-flow nasal oxygen technique	High-flow nasal oxygen technique	High-flow nasal oxygen will be applied to the patients through nasal openings using Optiflow system during anesthetic induction. Pulse oximetry and oxygen reserve index will be monitored continuously.
Mask ventilation technique	Mask ventilation technique	Oxygen will be supplied through the mouth and nose to the patients using facial mask during anesthetic induction. Pulse oximetry and oxygen reserve index will be monitored continuously.

Primary Outcome Measures

Name	Time	Method
Peak oxygen reserve index value	for 10 minutes during anesthetic induction. At Day 0.	Oxygen reserve index will be monitored continuously during anesthetic induction.

Secondary Outcome Measures

Name	Time	Method
The time to achieve the peak oxygen reserve index value	for 10 minutes during anesthetic induction. At Day 0.	Oxygen reserve index will be monitored continuously during anesthetic induction.

Trial Locations

Locations (1)

Severance Hospital, Yonsei University Health System; 🇰🇷 Seoul, Korea, Republic of