CTRI/2020/12/029965
Not yet recruiting
未知
Investigating the role of nicotinic neuromodulation in levodopa-induced dyskinesias â?? a multimodal study.
ational Brain Research Centre0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: G20- Parkinsons disease
- Sponsor
- ational Brain Research Centre
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •non\-smoker ( \>10 years)
- •\- able to provide informed consent
Exclusion Criteria
- •The subjects may not be eligible to participate if he/she \-
- •\-Has any neurological disorder (except PD in the patient group)
- •\-Has a current depressive episode, schizophrenia or bipolar disorder (self\-declared and screened with GHQ\-12 (Goldberg et al., 1978; Qin et al., 2018\))
- •\-Has had any head injury with loss of consciousness
- •\- Has had any seizures in the past
- •\-Has cognitive impairment (Mini Mental Status Examination (MMSE) test score \<25\)
- •\-Abuses drugs/alcohol
- •\-Is pregnant or nursing
- •Subjects will not be eligible for MRI scanning if they \-
- •\-Have non\-MRI compatible metal in the body such as a cardiac pacemaker, brain stimulator, surgical metal, cochlear implants, artificial heart valves or dental implants.
Outcomes
Primary Outcomes
Not specified
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