Investigating the role of nicotinic neuromodulation in levodopa-induced dyskinesias â?? a multimodal study.

ational Brain Research Centre0 sites0 target enrollmentStarted: TBDLast updated: November 24, 2021

Trial Snapshot

No summary available.

•The subjects may not be eligible to participate if he/she -
•-Has any neurological disorder (except PD in the patient group)
•-Has a current depressive episode, schizophrenia or bipolar disorder (self-declared and screened with GHQ-12 (Goldberg et al., 1978; Qin et al., 2018))
•-Has had any head injury with loss of consciousness
•- Has had any seizures in the past
•-Has cognitive impairment (Mini Mental Status Examination (MMSE) test score <25)
•-Abuses drugs/alcohol
•-Is pregnant or nursing
•Subjects will not be eligible for MRI scanning if they -
•-Have non-MRI compatible metal in the body such as a cardiac pacemaker, brain stimulator, surgical metal, cochlear implants, artificial heart valves or dental implants.
•-Are unable to lie flat on the back for the duration of the scan.
•-Have uncontrollable head movements.
•-Are claustrophobic.
•Subjects will not be eligible to undergo TMS if they â??
•-Have metal implants in the body such as brain stimulator, surgical metal, cochlear implants, cardiac pacemaker, intracardiac lines, implanted pumps or stimulators.

Sponsor

ational Brain Research Centre