Effect of rosouvastatin in CABG
Phase 4
Recruiting
- Conditions
- Atrial fibrillation.Paroxysmal atrial fibrillation
- Registration Number
- IRCT20180113038329N1
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 188
Inclusion Criteria
Patients undergoing elective CABG surgery
Exclusion Criteria
Patients with atrial fibrillation (AF) rhythm
The current liver disease (illness) including liver Cirrhosis, blood transaminase increment by 3 or more, Blood bilirubin concentration greater than 3 mg / dl
Recent use of antifungal medicines (azoles of CYP3A4 inhibitors), Protease inhibitor, Macrolides, Cyclosporine
History of myocardial infarction
Renal transplantation history
Renal insufficiency (serum creatinine> 2.5 mg/dl)
Cardiogenic shock
Pregnancy
Patients with complications during CABG surgery and after that (such as need for surgery for any reason, hemodynamic disorders, long intubation, rhythm disorders, need for shock, need for pericardiocentesis or chest tubing)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Atrial fibrillation. Timepoint: During the hospitalization period after coronary artery bypass graft surgery and one month later. Method of measurement: Cardiac monitoring, electrocardiogram.;Hospitalization period. Timepoint: Duration of admission after coronary artery bypass graft surgery. Method of measurement: Number of admission days after coronary artery bypass graft surgery.;Mortality. Timepoint: During the hospitalization period after coronary artery bypass graft surgery and one month later. Method of measurement: Registration of death in the case during hospitalization after coronary artery bypass graft surgery and post-clearance follow up to one month.
- Secondary Outcome Measures
Name Time Method