A randomised clinical trial assessing the additional value of ovarian hyperstimulation in intrauterine insemination for couples with an abnormal post-coital test.
Completed
- Conditions
- Subfertility.
- Registration Number
- NL-OMON21145
- Lead Sponsor
- OFO-projectt.a.v. B.W. MolAcademic Medical CenterCenter of Reporductive medicine, H4-213Postbus 226601100 DD AmsterdamPhone: 0031205663857Fax: 0031206963489e-mail: ofoproject@amc.uva.nl or b.mol1@chello.nl
- Brief Summary
Fertil Steril. 2007 Dec;88(6):1618-24. Epub 2007 Jun 11. <br> <br><br> Partly presented in an oral presentation at the Conjoint Annual Meeting of the American Societty for Reproductive Medicine and the Canadian Fertility and Andrology Society, ASRM/CFAS 2005, Montreal, Quebec, Canada.<br>
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
Couples were eligible if they had an abnormal PCT, either due to cervical hostility diagnosed by a well-timed, non-progressive PCT with normal semen parameters or due to a poor semen quality.
The spontaneous pregnancy chance in the next year, leaving the result of the PCT out of consideration, was < 30%.
Exclusion Criteria
All other subfertile couples.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint was ongoing pregnancy within three cycles of IUI. <br />Ongoing pregnancy was defined as the presence of foetal cardiac activity at transvaginal sonography at a gestational age of at least 12 weeks.
- Secondary Outcome Measures
Name Time Method Secondary endpoints were total number of clinical pregnancies, miscarriages and multiple pregnancies.