The effect of probiotic supplementation on patients' Anemia with chronic Renal failure on Hemodialysis.
- Conditions
- End stage kidney disease on hemodialysis.End stage kidney disease
- Registration Number
- IRCT2013072710325N2
- Lead Sponsor
- Deputy of Research andTechnology, Golestan University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 36
Over 17 years old;
Both sexess;
Erythropoietin therapy for at least 4 weeks;
Hemodialysis treatment for at least 6 months;
3 times dialysis per week and 4 hours per session;
Hemoglobin concentration <11g/dL in at least 3 episode;
CRP more than 10 mg/ lit;
No sever hyperparathyroidism;
No surgery or bleeding in the last 3 months;
Lack of Hemoglobin disorder including: Thalassemia or Sickle cell anemia;
Lack of iron deficiency;
Lack of folate and vitamin B12 deficiency;
Absence of active infection;
Lack of immune disorders such as Lupus erythematosus;
Absence of malignancy;
No Alcohol consuming;
No Consumption antibiotics in 10 days ago;
No Consumption corticosteroids;
Lack of viral infections: AIDS;
No Hospitalization;
Exclusion criteria:
Antibiotic therapy during the study;
Hospitalization;
Blood transfusion during the study;
Surgery during the study;
Change in drug program that it is effective on the anemia;
Change in dialysis program;
No Patient's tendency to stay in study;
Malignancy diagnosis during the study;
The presence of bleeding disorders during the study;
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemoglobin measurement. Timepoint: Before the intervention and three episode after intervantion With each month interval. Method of measurement: Laboratory equipment.
- Secondary Outcome Measures
Name Time Method Quantitative CRP. Timepoint: Before the intervention and three episode after intervantion With each month interval. Method of measurement: Laboratory equipment.;Blood presure. Timepoint: Three months before and three months after the intervention. Method of measurement: manometer.;Defecation pattern. Timepoint: Before the intervention and after the intervention three times with an interval of one month. Method of measurement: Bristol scale and patient statement.