Immunogenic Properties of Heated and Glycated Cow*s Milk Protein * Effect on Resolution of Cow*s Milk Allergy (iAGE study)

Completed

• Conditions: koemelkallergie; cow's milk allergy; cow's milk protein allergy

• Registration Number: NL-OMON50280
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

* Age: 3 up to 36 months.
* Children with a positive DBPCFC with CM. This is defined as a well-documented
DBPCFC with objective symptoms <48 hours that was performed *4 weeks prior to
inclusion in the study.
* Written informed consent by parents or legal guardian.

Exclusion Criteria

* Current participation or participation in the last 12 months in a medical
scientific interventional study for food allergy and/or with an investigational
new drug.
* Clinically significant immunological, cardiovascular or malignant disease.*
* Inability to discontinue antihistamines for skin testing and oral food
challenges.
* Caregiver not able to read and understand the Dutch language.
* Caregiver not able or willing to comply with the study procedures.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Development of tolerance (time to or percentage)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Adverse events.</p><br>