tility of whole blood based coagulation test (thrombelastography) in the assessment of abnormal bleeding conditions seen in severe infections.
Not Applicable
- Conditions
- Health Condition 1: D65- Disseminated intravascular coagulation [defibrination syndrome]
- Registration Number
- CTRI/2020/02/023514
- Lead Sponsor
- Kasturba Medical College Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All adult patients above the age of 18 years diagnosed with sepsis induced coagulopathy and admitted under the department of critical care medicine in Kasturba Hospital.
Exclusion Criteria
1.Patients discharged against Medical advice.
2.Death within 24 hours of admission into ICU.
3.Patients with existing bleeding disorders or platelet function disorder.
4.Patients who is on oral anticoagulants and anti-platelet drugs which will confound the hemostatic status.
5.Patients with diagnosed immune deficiency (hereditary / acquired).
6.Patients with history of Transfusion in last three months.
7.Patients who are diagnosed with chronic liver disorder.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢Compared to standard coagulation test, TEG may predict the in vivo hemostasis better.Timepoint: September 2021
- Secondary Outcome Measures
Name Time Method 1.Based on the diagnosis and categorization, developing a predictive score in the sepsis induced coagulopathy based on TEG might lead to a better patient care in future. <br/ ><br>2.TEG may be useful in categorizing sepsis induced coagulopathy into hypo-coagulable bleeding type or prothrombotic organ failure type. <br/ ><br>Timepoint: September 2021