Does the lowering in fat mobilisation during exercise lead to greater improvements in glycemic control in type 2 diabetes?
- Conditions
- Type 2 diabetes
- Registration Number
- NL-OMON22784
- Lead Sponsor
- niversiteit Maastricht Medical Centre
- Brief Summary
none
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Twelve male T2DM patients (fasting blood glucose level >125mg/dl, and/or HbA1c >6.5%) will be included. Subjects with following characteristics will be included: age 45-70 years, body mass index 27.5-35.0 kg/m², sedentary (<2 hours sport/week), treated by oral blood glucose lowering medication, no exogenous insulin therapy, no history of coronary events/revascularization, absence of chronic pulmonary, renal disease, gastric complaints/disease, and/or orthopedic disease that interferes with exercise, no involvement in exercise training and/or caloric restriction program for at least one year.
Exogenous insulin therapy, history of coronary events/revascularization, presence of chronic pulmonary, renal disease, gastric complaints/disease, and/or orthopedic disease that interferes with exercise, involvement in exercise training and/or caloric restriction program for at least one year
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24-hour glycemic control: serial measurements of blood glucose, insulin levels, and calculation of HOMA-IR index.
- Secondary Outcome Measures
Name Time Method Blood free fatty acid, triglyceride, and lactate levels.