Central effect of acupuncture at Yanglingquan based on acupoint specificity on food picture stimulation paradigm with gallstone disease: a randomized controlled trial.
- Conditions
- gallstone disease
- Registration Number
- ITMCTR2000003453
- Lead Sponsor
- Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Meet the diagnostic criteria for gallstone disease set by the EASL in 2016;
2. Aged between 18 and 60 years and right-handed;
3. have not taken any cholagogic drugs within 1 month;
4. not participating in any other clinical trials in the past three months;
5. having signed informed consent.
1. calculus in bile duct;
2. acute cholecystitis, acute suppurative, gangrenous, incarcerated cholecystitis and perforation of gallbladder with diffuse peritonitis, etc.;
3. with serious complications or primary diseases such as cardiovascular, liver, kidney, endocrine and hematopoietic system;
4. with severe digestive system diseases, such as peptic ulcer, upper gastrointestinal hemorrhage, gastric tumor, Crohn's disease, irritable bowel syndrome, etc;
5. WBC > 12*10^9/L with systemic inflammatory response;
6. having a history of corticosteroid treatment in the past month;
7. having a history of anti-infective drug therapy (excluding cephalosporins) in the past month;
8. with high anxiety and depression (SAS >= 70 or SDS >= 72) and those with mental illness;
9. with obvious headache, migraine, head injury history and obvious pain in other parts;
10. women being in pregnancy or lactation; or
11. having contraindications of MRI scans such as claustrophobia or implanted ferromagnetic metal;
12. with head space occupying disease.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method task fMRI data;
- Secondary Outcome Measures
Name Time Method appetite test;Numeric Rating Scale;