Effects of a Psycho-corporal Training on Postural and Cognitive Dual-task Performances in Patients With Schizophrenia

Not Applicable

Completed

• Conditions: Schizophrenia
• Interventions: Other: Movement group

• Registration Number: NCT03280810
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

Beside these well-known symptoms (positive symptoms (such as delirium and delusions), negative symptoms (such as affective flattening and impoverishment of speech), disorganized behavior, patients with schizophrenia show different kinds of cognitive alterations and motor abnormalities. In schizophrenia, postural impairment could increase the attentional cost of daily motor tasks, leading to a lack of attentional resources, essential to achieve complex cognitive tasks. The intrication of cognitive and postural processings (both impaired in schizophrenia) can be explored by using of a dual-task paradigm.

Detailed Description

This study assesses a psycho-corporal training (8 weeks psycho-corporal training) benefits on both postural (increased automation of balance control) and cognitive processings (smaller impact of the dual-task condition on attentional performances) in population of patients suffering from schizophrenia.

Study Timeline

• Study Start: 2013-12
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2017-09
• Study First Submitted: 2017-09-11
• Study First Submitted QC: 2017-09-11
• Study First Posted: 2017-09-13
• Last Update Submitted: 2017-09-13
• Last Update Posted: 2017-09-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• a DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) diagnosis of schizophrenia (men or women)
• Men or woman aged 18-55
• Patients with no change in antipsychotic medication and clinical status within four weeks prior to the study
• Affiliates or entitled to a social security scheme
• Have given their informed consent before participating in the study.

Exclusion Criteria

• Intelligence Quotient below 70 (score PM38)
• History of head trauma, neurological disease or not stabilized serious physical illness
• Disorders related to the use of a psychoactive substance, as defined by the DSM-IV (abuse, dependence or withdrawal) within 6 months.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Movement group	Movement group	patients with schizophrenia (experimental group) have psycho-corporal training once a week, during 1 hour and a half for a period of two months

Primary Outcome Measures

Name	Time	Method
the losses of postural and attentional control	At 8 weeks	To analyze the losses of postural and attentional control under dual-task condition.; Losses of postural and attentional control are calculated by one composite score named mu (Baddeley, Della Sala, Papagno, \& Spinnler, 1997).

Secondary Outcome Measures

Name	Time	Method
cognitive decrement	At 8 weeks	To compare mean values of the cognitive decrement between baseline and 8 weeks in which the Redundancy value of the responses sequence to the random number generation task were analyzed using RgCalc® software (Towse \& Neil, 1998).
postural decrement	At 8 weeks	To compare mean values of the postural decrement between baseline and 8 weeks in which the confidence Ellipse is used as main criteria to evaluate the participants balance ability postural sway platform (WIN-POSTURO Médicapteurs®).

Trial Locations

Locations (1)

Chu Saint-Etienne; 🇫🇷 St Etienne, France