Effects of Resistance Exercise on Metabolic Responses
- Conditions
- Inflammatory Response
- Registration Number
- NCT05051306
- Lead Sponsor
- National Taiwan Normal University
- Brief Summary
Healthy young adults will complete three trials in a randomized crossover counter-balanced order, including two different loads of resistance exercise and sedentary control. During each trial, blood samples will be collected.
The investigators hypothesized that high-load and low-load resistance exercise exert similar metabolic responses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 11
- Age: 20-30
- Healthy male
- Without experience of resistance training
- No acute or chronic musculoskeletal symptoms
- Smoking
- Alcohol or drug abuse
- Fail to conduct resistance exercise
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Changes in TG 4-hour during each study intervention TG mg/dL
Changes in uric acid 4-hour during each study intervention uric acid mg/dL.
Changes in glucose 4-hour during each study intervention glucose in mg/dL
Changes in insulin 4-hour during each study intervention insulin in mU/L
- Secondary Outcome Measures
Name Time Method Changes in NO 4-hour during each study intervention NO in µmol/L
Changes in biomarkers of inflammation 4-hour during each study intervention Biomarkers of inflammation will be measured such as IL-10 in pg/mL and IL-6 in pg/mL.
Changes in cortisol 4-hour during each study intervention cortisol in ng/mL
Changes in complete blood count 4-hour during each study intervention blood cell count in count per µL
Borgs Ratings of Perceived Exertion (RPE) 1-hour during each exercise intervention Borgs RPE is a method of estimating exertion rating, based on a 6 to 20 rating scale (6 being the no exertion at all, 20 being maximal exertion).
Changes in lactate 4-hour during each study intervention lactate in mmol/L
Changes in biomarkers of muscle damage 4-hour during each study intervention Biomarkers of muscle damage will be measured such as CK in U/L and LDH in U/L.
Heart rate (HR) 6-hour during each study intervention HR will be measured during each study intervention.
Changes in ET-1 4-hour during each study intervention ET-1 in pg/mL
Visual Analogue Scale (VAS) of appetite 6-hour during each study intervention Hunger, fullness, desire to eat, and prospective food consumption will be measured via VAS ratings, based on a 100 mm long scale (0 being "not at all", 100 being "extremely").
Changes in biomarkers of appetite 4-hour during each study intervention Biomarkers of appetite will be measured such as ghrelin in pg/mL and PYY in pg/mL.
Trial Locations
- Locations (1)
National Taiwan Normal University
🇨🇳Taipei, Taiwan
National Taiwan Normal University🇨🇳Taipei, Taiwan