Skip to main content
Clinical Trials/NCT02281331
NCT02281331
Completed
N/A

Evaluation of the Effects of a Combined Resistance and High-intensity Interval Exercise Training Program, Along With Nutritional Supplementation, on Strength and Physical Function in Older Men

McMaster University1 site in 1 country50 target enrollmentOctober 1, 2014
ConditionsAging

Overview

Phase
N/A
Intervention
Not specified
Conditions
Aging
Sponsor
McMaster University
Enrollment
50
Locations
1
Primary Endpoint
Muscle mass
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

As we age we tend to lose muscle mass and strength. These losses contribute to the increased incidence of falls and fractures, metabolic diseases such as type 2 diabetes, loss of independence and reduced quality of life in the elderly. As the number of seniors increases worldwide, it is becoming more and more important to develop strategies to counteract this loss of muscle mass and strength, and promote healthy aging. Fortunately, relatively simple lifestyle modifications are the most potent defense strategies. Exercises such as weight lifting and high-intensity interval exercise (HIIT), which consists of short, repeated bouts of vigorous aerobic exercise interspersed with period of rest, are the most effective in promoting gains in muscle mass and strength. Additionally, components of foods like whey (a protein found in milk), creatine (found in meat), calcium and vitamin D have been shown to independently increase strength. In this study, we are looking to determine how much we can increase muscle strength in older men who are put on an 12 week exercise training program that combines weight lifting and HIIT, and who consume a daily supplement that contains whey protein, creatine, calcium and vitamin D.

Detailed Description

Please see other documentation.

Registry
clinicaltrials.gov
Start Date
October 1, 2014
End Date
May 1, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Stuart Phillips

Principal Investigator

McMaster University

Eligibility Criteria

Inclusion Criteria

  • Sedentary (no participation in a structured exercise training program in past 6 months)
  • BMI between 18.5-30.0 kg/m2
  • Weight stable for past 6 months
  • Normal resting blood pressure, or stage I hypertension

Exclusion Criteria

  • Use of simvastatin or atorvastatin
  • Use of non-steroidal anti-inflammatory drugs
  • Injuries that prevent safe-participation in an exercise training program
  • Prescription blood thinners
  • Diabetes or other metabolic disorders
  • Cardiac or gastro-intestinal problems
  • Infectious disease or cancer

Outcomes

Primary Outcomes

Muscle mass

Time Frame: 12 weeks

DXA, ultrasound

Secondary Outcomes

  • Muscle protein synthesis(12 weeks)
  • Satellite cell number, density, type I/type II fibre specific satellite cells and myonuclear domain(12 weeks)
  • Glycemic control(12 weeks)
  • Cognitive function(12 weeks)

Study Sites (1)

Loading locations...

Similar Trials