PhaseI/II trial of neoadjvant chemoradiotherapy with docetaxel,CDDP and 5-Fluorouracil followed by surgery in patients with advanced esophageal cancer. - PhaseI/II trial of neoadjvant chemoradiotherapy with DCF in patients with advanced esophageal cancer.

Department of Surgical Oncology, Division of Clinical and Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University0 sites40 target enrollmentAugust 1, 2009

ConditionsEsophageal Cancer

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Esophageal Cancer
Sponsor: Department of Surgical Oncology, Division of Clinical and Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University
Enrollment: 40
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

August 1, 2009

End Date

November 1, 2014

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Department of Surgical Oncology, Division of Clinical and Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•1\.History of hypersensitivity to DOC, CDDP, 5\-FU, or polysorbate 80 2\.With severe complication 3\.Infection with fever elevation 4\.Motor paralysis, peripheral neuropathy or edema 5\.Pleural or pericardial effusion that requires treatment 6\.Simultaneous or metachronous (within 5 years) double cancers. 7\.Pregnant or lactating women 8\.Interstitial pneumonia or fibroid lung 9\.Psychosis