Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Phase 3

Recruiting

• Conditions: Atrial Fibrillation (AF)
• Interventions: Biological: Abelacimab; Drug: Placebo

• Registration Number: NCT05712200
• Lead Sponsor: Anthos Therapeutics, Inc.

Brief Summary

A study to evaluate the effect of abelacimab relative to placebo on the rate of ischemic stroke or systemic embolism (SE) in patients with Atrial Fibrillation (AF) who have been deemed by their responsible physicians or by their own decision to be unsuitable for oral anticoagulation therapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-27
• Study First Submitted: 2023-01-12
• Study First Submitted QC: 2023-01-25
• Study First Posted: 2023-02-03
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-16
• Last Update Posted: 2025-05-20
• Primary Completion: 2026-08
• Study Completion: 2026-10

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1900

Inclusion Criteria

• Patient is able to understand and has provided written informed consent to participate in the trial
• Diagnosed Atrial Fibrillation (AF) or atrial flutter (documented on an electrocardiogram (ECG) or monitor recording)
• Age 65-74 and a CHA2DS2VASc ≥4 OR age ≥75 and a CHA2DS2VASc ≥3
• Patient is judged by the responsible physician to be unsuitable for oral anticoagulation because the risks outweigh the benefits or the patient is unwilling to take oral anticoagulation AND this determination was made prior to and independent of the study
• At least 1 bleeding risk factor such as severe renal insufficiency, planned daily use of antiplatelet medication for the duration of the trial, history of bleeding from a critical area, or other conditions associated with increased risk of bleeding such as chronic nonsteroidal anti-inflammatory drug (NSAID) use, frailty or multiple falls
• Patient is judged by the responsible physician to be unsuitable for left atrial appendage (LAA) closure or occlusion device, an approved device is not available, or the patient is unwilling to undergo the procedure AND this determination was made prior to and independent of the study

Exclusion Criteria

• AF due to an ongoing acute reversible cause (e.g., cardiac surgery, pulmonary embolism (PE), untreated hyperthyroidism, alcohol use)
• Patients who within 60 days prior to randomization (1) received a vitamin K antagonists (VKA) (e.g., warfarin, phenprocoumon, acenocoumarol) or a direct oral anticoagulant (DOAC) such as, dabigatran, rivaroxaban, apixaban, or edoxaban or (2) were newly diagnosed with AF
• Patients with an intracranial or intraocular bleed within the 3 months prior to screening or any history of spontaneous intracerebral hemorrhage at any time in the absence of antithrombotic treatment
• Any stroke within 14 days before randomization or transient ischemic attack (TIA) within 3 days before randomization
• Mechanical heart valve or valve disease that is expected to require mechanical valve replacement intervention (surgical or invasive) during the course of the study

Other protocol defined Inclusion/Exclusion criteria may apply

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Abelacimab (MAA868)	Abelacimab	Patients will be randomized in a 1:1 ratio to receive abelacimab 150 mg subcutaneous (SC) or matching placebo once monthly.
Placebo	Placebo	Patients will be randomized in a 1:1 ratio to receive abelacimab 150 mg subcutaneous (SC) or matching placebo once monthly.

Primary Outcome Measures

Name	Time	Method
Efficacy: Time to first event of ischemic stroke or systemic embolism (SE)	Up to 30 months
Safety: Time to first occurrence of Bleeding Academic Research Consortium (BARC) type 3c/5 bleeding	Up to 30 months

Secondary Outcome Measures

Name	Time	Method
Efficacy: All-cause mortality	Up to 30 months
Efficacy: Cardiovascular (CV) mortality	Up to 30 months
Efficacy: Time to first event of ischemic stroke, systemic embolism (SE), or Bleeding Academic Research Consortium (BARC) type 3c/5 bleeding event	Up to 30 months
Efficacy: Time to first event of ischemic stroke, systemic embolism (SE), myocardial infarctions (MI), venous thromboembolism (VTE), or acute limb ischemia	Up to 30 months	Abelacimab versus placebo with regard to the composite of ischemic stroke, SE, MI, VTE, or acute limb ischemia
Time to first event of ischemic stroke, systemic embolism (SE), myocardial infarctions (MI), venous thromboembolism (VTE), acute limb ischemia, or International Society on Thrombosis and Haemostasis (ISTH) major bleeding	Up to 30 months	Abelacimab versus placebo with regard to net clinical outcome defined as the composite of ischemic stroke, SE, MI, VTE, acute limb ischemia, or International Society on Thrombosis and Haemostasis (ISTH) major bleeding

Trial Locations

Locations (480)

Anthos Investigative Site 1537; 🇧🇷 Rio De Janeiro, Brazil

Anthos Investigative Site 1510; 🇧🇷 Salvador, Brazil

Anthos Investigative Site 1521; 🇧🇷 Salvador, Brazil

Anthos Investigative Site 1534; 🇧🇷 São Paulo, Brazil

Anthos Investigative Site 6024; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6023; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6010; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6015; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6020; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6001; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6017; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6012; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6002; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 1815; 🇨🇳 Ningbo, China

Anthos Investigative Site 2316; 🇮🇳 Nagpur, India

Anthos Investigative Site 8011; 🇮🇹 Roma, Italy

Anthos Investigative Site 8002; 🇮🇹 Roma, Italy

Anthos Investigative Site 1427; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 8004; 🇮🇹 Saronno, Italy

Anthos Investigative Site 1434; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1419; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1040; 🇺🇸 Birmingham, Alabama, United States

Anthos Investigative Site 1041; 🇺🇸 Mobile, Alabama, United States

Anthos Investigative Site 1089; 🇺🇸 Gilbert, Arizona, United States

Anthos Investigative Site 1099; 🇺🇸 Peoria, Arizona, United States

Anthos Investigative Site 9906; 🇺🇸 Phoenix, Arizona, United States

Anthos Investigative Site 1078; 🇺🇸 Loma Linda, California, United States

Anthos Investigative Site 1077; 🇺🇸 Los Angeles, California, United States

Anthos Investigative Site 1015; 🇺🇸 Northridge, California, United States

Anthos Investigative Site 1070; 🇺🇸 Redding, California, United States

Anthos Investigative Site 1071; 🇺🇸 San Dimas, California, United States

Anthos Investigative Site 1076; 🇺🇸 Santa Ana, California, United States

Anthos Investigative Site 9908; 🇺🇸 South Gate, California, United States

Anthos Investigative Site 9907; 🇺🇸 Vista, California, United States

Anthos Investigative Site 1095; 🇺🇸 Aurora, Colorado, United States

Anthos Investigative Site 1049; 🇺🇸 Denver, Colorado, United States

Anthos Investigative Site 1012; 🇺🇸 Stamford, Connecticut, United States

Anthos Investigative Site 1013; 🇺🇸 Boca Raton, Florida, United States

Anthos Investigative Site 1025; 🇺🇸 Clearwater, Florida, United States

Anthos Investigative Site 1022; 🇺🇸 Clearwater, Florida, United States

Anthos Investigative Site 1019; 🇺🇸 Daytona Beach, Florida, United States

Anthos Investigative Site 1083; 🇺🇸 Hollywood, Florida, United States

Anthos Investigative Site 1008; 🇺🇸 Jacksonville, Florida, United States

Anthos Investigative Site 9904; 🇺🇸 Lake Mary, Florida, United States

Anthos Investigative Site 1093; 🇺🇸 Lutz, Florida, United States

Anthos Investigative Site 1072; 🇺🇸 Miami Lakes, Florida, United States

Anthos Investigative Site 1067; 🇺🇸 Ormond Beach, Florida, United States

Anthos Investigative Site 1026; 🇺🇸 Safety Harbor, Florida, United States

Anthos Investigative Site 1002; 🇺🇸 Saint Augustine, Florida, United States

Anthos Investigative Site 1004; 🇺🇸 Saint Augustine, Florida, United States

Anthos Investigative Site 1044; 🇺🇸 Tamarac, Florida, United States

Anthos Investigative Site 1046; 🇺🇸 Tampa, Florida, United States

Anthos Investigative Site 9915; 🇺🇸 Evansville, Indiana, United States

Anthos Investigative Site 1016; 🇺🇸 Wichita, Kansas, United States

Anthos Investigative Site 1088; 🇺🇸 Tamarac, Florida, United States

Anthos Investigative Site 9911; 🇺🇸 The Villages, Florida, United States

Anthos Investigative Site 1052; 🇺🇸 Lithonia, Georgia, United States

Anthos Investigative Site 1033; 🇺🇸 Macon, Georgia, United States

Anthos Investigative Site 1042; 🇺🇸 Norcross, Georgia, United States

Anthos Investigative Site 1003; 🇺🇸 Suwanee, Georgia, United States

Anthos Investigative Site 1098; 🇺🇸 Merrillville, Indiana, United States

Anthos Investigative Site 1030; 🇺🇸 Park Ridge, Illinois, United States

Anthos Investigative Site 1039; 🇺🇸 Baltimore, Maryland, United States

Anthos Investigative Site 1023; 🇺🇸 Lanham, Maryland, United States

Anthos Investigative Site 1028; 🇺🇸 Rockville, Maryland, United States

Anthos Investigative Site 1082; 🇺🇸 Boston, Massachusetts, United States

Anthos Investigative Site 1006; 🇺🇸 Alexandria, Louisiana, United States

Anthos Investigative Site 1043; 🇺🇸 Shreveport, Louisiana, United States

Anthos Investigative Site 1054; 🇺🇸 Bangor, Maine, United States

Anthos Investigative Site 1021; 🇺🇸 Lansing, Michigan, United States

Anthos Investigative Site 1059; 🇺🇸 Southgate, Michigan, United States

Anthos Investigative Site 1017; 🇺🇸 Tupelo, Mississippi, United States

Anthos Investigative Site 1080; 🇺🇸 Kansa City, Missouri, United States

Anthos Investigative Site 1066; 🇺🇸 Lincoln, Nebraska, United States

Anthos Investigative Site 1036; 🇺🇸 Las Vegas, Nevada, United States

Anthos Investigative Site 9914; 🇺🇸 Las Vegas, Nevada, United States

Anthos Investigative Site 1094; 🇺🇸 Englewood, New Jersey, United States

Anthos Investigative Site 9905; 🇺🇸 Brooklyn, New York, United States

Anthos Investigative Site 1014; 🇺🇸 Middletown, New York, United States

Anthos Investigative Site 1037; 🇺🇸 Rosedale, New York, United States

Anthos Investigative Site 9924; 🇺🇸 Westfield, New York, United States

Anthos Investigative Site 1065; 🇺🇸 Cary, North Carolina, United States

Anthos Investigative Site 1005; 🇺🇸 Charlotte, North Carolina, United States

Anthos Investigative Site 9912; 🇺🇸 Durham, North Carolina, United States

Anthos Investigative Site 1048; 🇺🇸 Fayetteville, North Carolina, United States

Anthos Investigative Site 1035; 🇺🇸 Henderson, North Carolina, United States

Anthos Investigative Site 1001; 🇺🇸 Lenoir, North Carolina, United States

Anthos Investigative Site 9902; 🇺🇸 Beavercreek, Ohio, United States

Anthos Investigative Site 1075; 🇺🇸 Portland, Oregon, United States

Anthos Investigative Site 1074; 🇺🇸 Bristol, Pennsylvania, United States

Anthos Investigative Site 1087; 🇺🇸 Horsham, Pennsylvania, United States

Anthos Investigative Site 1032; 🇺🇸 Rock HIll, South Carolina, United States

Anthos Investigative Site 1050; 🇺🇸 Elizabethton, Tennessee, United States

Anthos Investigative Site 1057; 🇺🇸 Germantown, Tennessee, United States

Anthos Investigative Site 1056; 🇺🇸 Memphis, Tennessee, United States

Anthos Investigative Site 9913; 🇺🇸 Beaumont, Texas, United States

Anthos Investigative Site 1091; 🇺🇸 El Paso, Texas, United States

Anthos Investigative Site 1069; 🇺🇸 Houston, Texas, United States

Anthos Investigative Site 1068; 🇺🇸 Houston, Texas, United States

Anthos Investigative Site 1097; 🇺🇸 Houston, Texas, United States

Anthos Investigative Site 9903; 🇺🇸 Houston, Texas, United States

Anthos Investigative Site 1053; 🇺🇸 Houston, Texas, United States

Anthos Investigative Site 1064; 🇺🇸 Houston, Texas, United States

Anthos Investigative Site 9901; 🇺🇸 Laredo, Texas, United States

Anthos Investigative Site 1063; 🇺🇸 McAllen, Texas, United States

Anthos Investigative Site 1096; 🇺🇸 McKinney, Texas, United States

Anthos Investigative Site 1079; 🇺🇸 McKinney, Texas, United States

Anthos Investigative Site 1024; 🇺🇸 Odessa, Texas, United States

Anthos Investigative Site 1085; 🇺🇸 Port Arthur, Texas, United States

Anthos Investigative Site 1090; 🇺🇸 Sugar Land, Texas, United States

Anthos Investigative Site 1011; 🇺🇸 Tomball, Texas, United States

Anthos Investigative Site 9916; 🇺🇸 Tyler, Texas, United States

Anthos Investigative Site 9910; 🇺🇸 Victoria, Texas, United States

Anthos Investigative Site 1060; 🇺🇸 Waco, Texas, United States

Anthos Investigative Site 9909; 🇺🇸 Webster, Texas, United States

Anthos Investigative Site 1092; 🇺🇸 Wylie, Texas, United States

Anthos Investigative Site 1084; 🇺🇸 American Fork, Utah, United States

Anthos Investigative Site 1031; 🇺🇸 Bountiful, Utah, United States

Anthos Investigative Site 1029; 🇺🇸 Holladay, Utah, United States

Anthos Investigative Site 1038; 🇺🇸 Pleasant View, Utah, United States

Anthos Investigative Site 1034; 🇺🇸 Roy, Utah, United States

Anthos Investigative Site 1018; 🇺🇸 Falls Church, Virginia, United States

Anthos Investigative Site 1010; 🇺🇸 Manassas, Virginia, United States

Anthos Investigative Site 1009; 🇺🇸 Roanoke, Virginia, United States

Anthos Investigative Site 1073; 🇺🇸 Tacoma, Washington, United States

Anthos Investigative Site 1411; 🇦🇷 Buenos Aires, Argentina

Anthos Investigative Site 1409; 🇦🇷 Ciudad Autónoma Buenos Aires, Argentina

Anthos Investigative Site 1410; 🇦🇷 Ciudad Autónoma de Buenos Aire, Argentina

Anthos Investigative Site 1423; 🇦🇷 Ciudad Autónoma de Buenos Aire, Argentina

Anthos Investigative Site 1429; 🇦🇷 Coronel Suárez, Argentina

Anthos Investigative Site 1420; 🇦🇷 Corrientes, Argentina

Anthos Investigative Site 1407; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1414; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1418; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1424; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1431; 🇦🇷 Córdoba, Argentina

Anthos Investigative Site 1415; 🇦🇷 Ramos Mejia, Argentina

Anthos Investigative Site 1403; 🇦🇷 Salta, Argentina

Anthos Investigative Site 1425; 🇦🇷 San Luis, Argentina

Anthos Investigative Site 1404; 🇦🇷 San Miguel De Tucumán, Argentina

Anthos Investigative Site 1435; 🇦🇷 San Miguel De Tucumán, Argentina

Anthos Investigative Site 1518; 🇧🇷 Aracaju, Brazil

Anthos Investigative Site 1527; 🇧🇷 Belo Horizonte, Brazil

Anthos Investigative Site 1528; 🇧🇷 Belo Horizonte, Brazil

Anthos Investigative Site 1516; 🇧🇷 Belo Horizonte, Brazil

Anthos Investigative Site 1507; 🇧🇷 Belo Horizonte, Brazil

Anthos Investigative Site 1513; 🇧🇷 Blumenau, Brazil

Anthos Investigative Site 1505; 🇧🇷 Blumenau, Brazil

Anthos Investigative Site 1535; 🇧🇷 Brasília, Brazil

Anthos Investigative Site 1501; 🇧🇷 Campina Grande Do Sul, Brazil

Anthos Investigative Site 1503; 🇧🇷 Campinas, Brazil

Anthos Investigative Site 1522; 🇧🇷 Campinas, Brazil

Anthos Investigative Site 1520; 🇧🇷 Campo Grande, Brazil

Anthos Investigative Site 1532; 🇧🇷 Canoas, Brazil

Anthos Investigative Site 1526; 🇧🇷 Caxias Do Sul, Brazil

Anthos Investigative Site 1542; 🇧🇷 Colatina, Brazil

Anthos Investigative Site 1540; 🇧🇷 Curitiba, Brazil

Anthos Investigative Site 1509; 🇧🇷 Curitiba, Brazil

Anthos Investigative Site 1525; 🇧🇷 Goiânia, Brazil

Anthos Investigative Site 1502; 🇧🇷 Marília, Brazil

Anthos Investigative Site 1533; 🇧🇷 Passo Fundo, Brazil

Anthos Investigative Site 1517; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1519; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1506; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1530; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1512; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1524; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1508; 🇧🇷 Porto Alegre, Brazil

Anthos Investigative Site 1531; 🇧🇷 Recife, Brazil

Anthos Investigative Site 1515; 🇧🇷 Ribeirão Preto, Brazil

Anthos Investigative Site 1536; 🇧🇷 Ribeirão Preto, Brazil

Anthos Investigative Site 1511; 🇧🇷 São Paulo, Brazil

Anthos Investigative Site 1538; 🇧🇷 São Paulo, Brazil

Anthos Investigative Site 1539; 🇧🇷 São Paulo, Brazil

Anthos Investigative Site 1529; 🇧🇷 São Paulo, Brazil

Anthos Investigative Site 1514; 🇧🇷 Tatuí, Brazil

Anthos Investigative Site 1541; 🇧🇷 Teresina, Brazil

Anthos Investigative Site 1504; 🇧🇷 Votuporanga, Brazil

Anthos Investigative Site 6014; 🇧🇬 Blagoevgrad, Bulgaria

Anthos Investigative Site 6026; 🇧🇬 Burgas, Bulgaria

Anthos Investigative Site 6019; 🇧🇬 Gabrovo, Bulgaria

Anthos Investigative Site 6018; 🇧🇬 Haskovo, Bulgaria

Anthos Investigative Site 6013; 🇧🇬 Panagyurishte, Bulgaria

Anthos Investigative Site 6025; 🇧🇬 Pazardzhik, Bulgaria

Anthos Investigative Site 6006; 🇧🇬 Pleven, Bulgaria

Anthos Investigative Site 6003; 🇧🇬 Pleven, Bulgaria

Anthos Investigative Site 6007; 🇧🇬 Plovdiv, Bulgaria

Anthos Investigative Site 6008; 🇧🇬 Plovdiv, Bulgaria

Anthos Investigative Site 6009; 🇧🇬 Plovdiv, Bulgaria

Anthos Investigative Site 6004; 🇧🇬 Plovdiv, Bulgaria

Anthos Investigative Site 6021; 🇧🇬 Plovdiv, Bulgaria

Anthos Investigative Site 6027; 🇧🇬 Sliven, Bulgaria

Anthos Investigative Site 6022; 🇧🇬 Smolyan, Bulgaria

Anthos Investigative Site 6030; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6028; 🇧🇬 Sofia, Bulgaria

Anthos Investigative Site 6011; 🇧🇬 Stara Zagora, Bulgaria

Anthos Investigative Site 2012; 🇨🇦 Mira Road, Nova Scotia, Canada

Anthos Investigative Site 2003; 🇨🇦 Cambridge, Ontario, Canada

Anthos Investigative Site 2007; 🇨🇦 Chicoutimi, Quebec, Canada

Anthos Investigative Site 2010; 🇨🇦 Sherbrooke, Quebec, Canada

Anthos Investigative Site 2016; 🇨🇦 Abbotsford, Canada

Anthos Investigative Site 2019; 🇨🇦 Brampton, Canada

Anthos Investigative Site 2015; 🇨🇦 Edmonton, Canada

Anthos Investigative Site 2018; 🇨🇦 Greenfield Park, Canada

Anthos Investigative Site 2005; 🇨🇦 Halifax, Canada

Anthos Investigative Site 2014; 🇨🇦 Montréal, Canada

Anthos Investigative Site 2004; 🇨🇦 New Westminster, Canada

Anthos Investigative Site 2021; 🇨🇦 North Vancouver, Canada

Anthos Investigative Site 2002; 🇨🇦 Québec, Canada

Anthos Investigative Site 2024; 🇨🇦 Saint Catharines, Canada

Anthos Investigative Site 2006; 🇨🇦 Saint-Jérôme, Canada

Anthos Investigative Site 2022; 🇨🇦 Thunder Bay, Canada

Anthos Investigative Site 2017; 🇨🇦 Toronto, Canada

Anthos Investigative Site 2020; 🇨🇦 Toronto, Canada

Anthos Investigative Site 2023; 🇨🇦 Toronto, Canada

Anthos Investigative Site 1605; 🇨🇱 Concepción, Chile

Anthos Investigative Site 1606; 🇨🇱 Independencia, Chile

Anthos Investigative Site 1604; 🇨🇱 Providencia, Chile

Anthos Investigative Site 1607; 🇨🇱 San Bernardo, Chile

Anthos Investigative Site 1609; 🇨🇱 San Miguel, Chile

Anthos Investigative Site 1608; 🇨🇱 Santiago, Chile

Anthos Investigative Site 1610; 🇨🇱 Talcahuano, Chile

Anthos Investigative Site 1603; 🇨🇱 Temuco, Chile

Anthos Investigative Site 1602; 🇨🇱 Temuco, Chile

Anthos Investigative Site 1601; 🇨🇱 Viña Del Mar, Chile

Anthos Investigative Site 1818; 🇨🇳 Changchun, China

Anthos Investigative Site 1810; 🇨🇳 Changsha, China

Anthos Investigative Site 1811; 🇨🇳 Changsha, China

Anthos Investigative Site 1802; 🇨🇳 Chengdu, China

Anthos Investigative Site 1809; 🇨🇳 Haidian, China

Anthos Investigative Site 1801; 🇨🇳 Hangzhou, China

Anthos Investigative Site 1808; 🇨🇳 Hangzhou, China

Anthos Investigative Site 1816; 🇨🇳 Jinan, China

Anthos Investigative Site 1804; 🇨🇳 Lianyungang, China

Anthos Investigative Site 1814; 🇨🇳 Luoyang, China

Anthos Investigative Site 1817; 🇨🇳 Nanchang, China

Anthos Investigative Site 1820; 🇨🇳 Nanchang, China

Anthos Investigative Site 1803; 🇨🇳 Nanjing, China

Anthos Investigative Site 1819; 🇨🇳 Shijiazhuang, China

Anthos Investigative Site 1812; 🇨🇳 Tianjin, China

Anthos Investigative Site 1813; 🇨🇳 Yangzhou, China

Anthos Investigative Site 1805; 🇨🇳 Yinchuan, China

Anthos Investigative Site 3002; 🇨🇿 Brandýs Nad Labem, Czechia

Anthos Investigative Site 3006; 🇨🇿 Liberec, Czechia

Anthos Investigative Site 3007; 🇨🇿 Ostrava - Poruba, Czechia

Anthos Investigative Site 3001; 🇨🇿 Poděbrady, Czechia

Anthos Investigative Site 3003; 🇨🇿 Prague, Czechia

Anthos Investigative Site 3005; 🇨🇿 Praha, Czechia

Anthos Investigative Site 3004; 🇨🇿 Praha, Czechia

Anthos Investigative Site 3010; 🇨🇿 Praha, Czechia

Anthos Investigative Site 3009; 🇨🇿 Trutnov, Czechia

Anthos Investigative Site 3011; 🇨🇿 Ústí Nad Labem, Czechia

Anthos Investigative Site 2203; 🇪🇪 Tallinn, Estonia

Anthos Investigative Site 2202; 🇪🇪 Tallinn, Estonia

Anthos Investigative Site 2201; 🇪🇪 Tallinn, Estonia

Anthos Investigative Site 7006; 🇩🇪 Altenburg, Germany

Anthos Investigative Site 7014; 🇩🇪 Berlin, Germany

Anthos Investigative Site 7004; 🇩🇪 Dresden, Germany

Anthos Investigative Site 7012; 🇩🇪 Hamburg, Germany

Anthos Investigative Site 7003; 🇩🇪 Hamburg, Germany

Anthos Investigative Site 7013; 🇩🇪 Hannover, Germany

Anthos Investigative Site 7009; 🇩🇪 Ludwigshafen, Germany

Anthos Investigative Site 7002; 🇩🇪 Markkleeberg, Germany

Anthos Investigative Site 7007; 🇩🇪 Paderborn, Germany

Anthos Investigative Site 7001; 🇩🇪 Schwerin, Germany

Anthos Investigative Site 4015; 🇭🇺 Budapest, Hungary

Anthos Investigative Site 4006; 🇭🇺 Budapest, Hungary

Anthos Investigative Site 4009; 🇭🇺 Budapest, Hungary

Anthos Investigative Site 4002; 🇭🇺 Békéscsaba, Hungary

Anthos Investigative Site 4011; 🇭🇺 Gyöngyös, Hungary

Anthos Investigative Site 4012; 🇭🇺 Kaposvar, Hungary

Anthos Investigative Site 4007; 🇭🇺 Kistarcsa, Hungary

Anthos Investigative Site 4005; 🇭🇺 Nyíregyháza, Hungary

Anthos Investigative Site 4010; 🇭🇺 Pécs, Hungary

Anthos Investigative Site 4017; 🇭🇺 Szeged, Hungary

Anthos Investigative Site 4016; 🇭🇺 Veszprém, Hungary

Anthos Investigative Site 4008; 🇭🇺 Zalaegerszeg, Hungary

Anthos Investigative Site 2310; 🇮🇳 Ahmedabad, India

Anthos Investigative Site 2320; 🇮🇳 Ahmedabad, India

Anthos Investigative Site 2311; 🇮🇳 Bangalore, India

Anthos Investigative Site 2318; 🇮🇳 Bhubaneswar, India

Anthos Investigative Site 2303; 🇮🇳 Chandigarh, India

Anthos Investigative Site 2324; 🇮🇳 Chennai, India

Anthos Investigative Site 2325; 🇮🇳 Chennai, India

Anthos Investigative Site 2328; 🇮🇳 Dehradun, India

Anthos Investigative Site 2308; 🇮🇳 Ghaziabad, India

Anthos Investigative Site 2306; 🇮🇳 Jaipur, India

Anthos Investigative Site 2304; 🇮🇳 Kochi, India

Anthos Investigative Site 2314; 🇮🇳 Kolkata, India

Anthos Investigative Site 2326; 🇮🇳 Mangaluru, India

Anthos Investigative Site 2329; 🇮🇳 Meerut, India

Anthos Investigative Site 2313; 🇮🇳 Mumbai, India

Anthos Investigative Site 2315; 🇮🇳 Nagpur, India

Anthos Investigative Site 2307; 🇮🇳 New Delhi, India

Anthos Investigative Site 2301; 🇮🇳 New Delhi, India

Anthos Investigative Site 2319; 🇮🇳 New Delhi, India

Anthos Investigative Site 2305; 🇮🇳 Pune, India

Anthos Investigative Site 2317; 🇮🇳 Pune, India

Anthos Investigative Site 2309; 🇮🇳 Secunderabad, India

Anthos Investigative Site 2312; 🇮🇳 Visakhapatnam, India

Anthos Investigative Site 2321; 🇮🇳 Visakhapatnam, India

Anthos Investigative Site 1210; 🇮🇱 Afula, Israel

Anthos Investigative Site 1205; 🇮🇱 Ashkelon, Israel

Anthos Investigative Site 1206; 🇮🇱 Hadera, Israel

Anthos Investigative Site 1211; 🇮🇱 Haifa, Israel

Anthos Investigative Site 1201; 🇮🇱 Haifa, Israel

Anthos Investigative Site 1209; 🇮🇱 H̱olon, Israel

Anthos Investigative Site 1204; 🇮🇱 Kfar Saba, Israel

Anthos Investigative Site 1202; 🇮🇱 Nahariya, Israel

Anthos Investigative Site 1207; 🇮🇱 Petah tikva, Israel

Anthos Investigative Site 1203; 🇮🇱 Reẖovot, Israel

Anthos Investigative Site 1208; 🇮🇱 Zefat, Israel

Anthos Investigative Site 8016; 🇮🇹 Ancona, Italy

Anthos Investigative Site 8003; 🇮🇹 Bologna, Italy

Anthos Investigative Site 8015; 🇮🇹 Brescia, Italy

Anthos Investigative Site 8019; 🇮🇹 Caserta, Italy

Anthos Investigative Site 8008; 🇮🇹 Catanzaro, Italy

Anthos Investigative Site 8021; 🇮🇹 Cinisello Balsamo, Italy

Anthos Investigative Site 8013; 🇮🇹 Lecco, Italy

Anthos Investigative Site 8001; 🇮🇹 Milano, Italy

Anthos Investigative Site 8007; 🇮🇹 Milan, Italy

Anthos Investigative Site 8017; 🇮🇹 Palermo, Italy

Anthos Investigative Site 8025; 🇮🇹 Pisa, Italy

Anthos Investigative Site 8010; 🇮🇹 Roma, Italy

Anthos Investigative Site 8005; 🇮🇹 Sesto San Giovanni, Italy

Anthos Investigative Site 8014; 🇮🇹 Torino, Italy

Anthos Investigative Site 8006; 🇮🇹 Varese, Italy

Anthos Investigative Site 8009; 🇮🇹 Vittoria, Italy

Anthos Investigative Site 1923; 🇯🇵 Akashi, Japan

Anthos Investigative Site 1908; 🇯🇵 Chikushino-shi, Japan

Anthos Investigative Site 1902; 🇯🇵 Chuo-Ku, Japan

Anthos Investigative Site 1920; 🇯🇵 Funabashi-Shi, Japan

Anthos Investigative Site 1910; 🇯🇵 Hamada-shi, Japan

Anthos Investigative Site 1924; 🇯🇵 Hamamatsu, Japan

Anthos Investigative Site 1906; 🇯🇵 Himeji-Shi, Japan

Anthos Investigative Site 1911; 🇯🇵 Imabari-shi, Japan

Anthos Investigative Site 1912; 🇯🇵 Isehara-Shi, Japan

Anthos Investigative Site 1921; 🇯🇵 Koto-Ku, Japan

Anthos Investigative Site 1915; 🇯🇵 Kure-shi, Japan

Anthos Investigative Site 1931; 🇯🇵 Matsue, Japan

Anthos Investigative Site 1903; 🇯🇵 Matsumoto-Shi, Japan

Anthos Investigative Site 1907; 🇯🇵 Nagano-Shi, Japan

Anthos Investigative Site 1929; 🇯🇵 Naha, Japan

Anthos Investigative Site 1922; 🇯🇵 Sapporo-shi, Japan

Anthos Investigative Site 1904; 🇯🇵 Sendai-shi, Japan

Anthos Investigative Site 1913; 🇯🇵 Shimonoseki-shi, Japan

Anthos Investigative Site 1914; 🇯🇵 Tachikawa-shi, Japan

Anthos Investigative Site 1909; 🇯🇵 Tochigi, Japan

Anthos Investigative Site 1925; 🇯🇵 Tokushima, Japan

Anthos Investigative Site 1928; 🇯🇵 Toyama, Japan

Anthos Investigative Site 1927; 🇯🇵 Tōon, Japan

Anthos Investigative Site 1901; 🇯🇵 Urayasu, Japan

Anthos Investigative Site 1917; 🇯🇵 Uwajima-Shi, Japan

Anthos Investigative Site 1918; 🇯🇵 Yokohama-shi, Japan

Anthos Investigative Site 1919; 🇯🇵 Yokohama-Shi, Japan

Anthos Investigative Site 1916; 🇯🇵 Yokohama-Shi, Japan

Anthos Investigative Site 1926; 🇯🇵 Ōmihachiman, Japan

Anthos Investigative Site 2103; 🇱🇻 Baldone, Latvia

Anthos Investigative Site 2109; 🇱🇻 Balvi, Latvia

Anthos Investigative Site 2107; 🇱🇻 Daugavpils, Latvia

Anthos Investigative Site 2108; 🇱🇻 Limbazi, Latvia

Anthos Investigative Site 2110; 🇱🇻 Riga, Latvia

Anthos Investigative Site 2101; 🇱🇻 Riga, Latvia

Anthos Investigative Site 2105; 🇱🇻 Riga, Latvia

Anthos Investigative Site 2102; 🇱🇻 Riga, Latvia

Anthos Investigative Site 2111; 🇱🇻 Sigulda, Latvia

Anthos Investigative Site 2104; 🇱🇻 Valmiera, Latvia

Anthos Investigative Site 2106; 🇱🇻 Valmiera, Latvia

Anthos Investigative Site 1701; 🇲🇽 Aguascalientes, Mexico

Anthos Investigative Site 1707; 🇲🇽 Aguascalientes, Mexico

Anthos Investigative Site 1713; 🇲🇽 Aguascalientes, Mexico

Anthos Investigative Site 1721; 🇲🇽 Chihuahua, Mexico

Anthos Investigative Site 1712; 🇲🇽 Ciudad De México, Mexico

Anthos Investigative Site 1703; 🇲🇽 Culiacán, Mexico

Anthos Investigative Site 1715; 🇲🇽 Guadalajara, Mexico

Anthos Investigative Site 1711; 🇲🇽 Guerrero, Mexico

Anthos Investigative Site 1704; 🇲🇽 Monterrey, Mexico

Anthos Investigative Site 1705; 🇲🇽 Monterrey, Mexico

Anthos Investigative Site 1719; 🇲🇽 Monterrey, Mexico

Anthos Investigative Site 1702; 🇲🇽 Querétaro, Mexico

Anthos Investigative Site 1718; 🇲🇽 San Luis Potosí, Mexico

Anthos Investigative Site 1716; 🇲🇽 Tlalpan, Mexico

Anthos Investigative Site 1706; 🇲🇽 Veracruz, Mexico

Anthos Investigative Site 1708; 🇲🇽 Veracruz, Mexico

Anthos Investigative Site 1709; 🇲🇽 Xalapa, Mexico

Anthos Investigative Site 5022; 🇵🇱 Czeladź, Poland

Anthos Investigative Site 5034; 🇵🇱 Gdynia, Poland

Anthos Investigative Site 5003; 🇵🇱 Katowice, Poland

Anthos Investigative Site 5009; 🇵🇱 Katowice, Poland

Anthos Investigative Site 5030; 🇵🇱 Katowice, Poland

Anthos Investigative Site 5005; 🇵🇱 Katowice, Poland

Anthos Investigative Site 5016; 🇵🇱 Kraków, Poland

Anthos Investigative Site 5018; 🇵🇱 Kraków, Poland

Anthos Investigative Site 5032; 🇵🇱 Legnica, Poland

Anthos Investigative Site 5023; 🇵🇱 Lublin, Poland

Anthos Investigative Site 5006; 🇵🇱 Lublin, Poland

Anthos Investigative Site 5008; 🇵🇱 Olsztyn, Poland

Anthos Investigative Site 5025; 🇵🇱 Oświęcim, Poland

Anthos Investigative Site 5002; 🇵🇱 Przemyśl, Poland

Anthos Investigative Site 5004; 🇵🇱 Rzeszów, Poland

Anthos Investigative Site 5001; 🇵🇱 Tychy, Poland

Anthos Investigative Site 5014; 🇵🇱 Warszawa, Poland

Anthos Investigative Site 5017; 🇵🇱 Warszawa, Poland

Anthos Investigative Site 5011; 🇵🇱 Warszawa, Poland

Anthos Investigative Site 5015; 🇵🇱 Warszawa, Poland

Anthos Investigative Site 5019; 🇵🇱 Wrocław, Poland

Anthos Investigative Site 5007; 🇵🇱 Wrocław, Poland

Anthos Investigative Site 5024; 🇵🇱 Zabrze, Poland

Anthos Investigative Site 5012; 🇵🇱 Łódź, Poland

Anthos Investigative Site 5028; 🇵🇱 Łódź, Poland

Anthos Investigative Site 9022; 🇷🇴 Baloteşti, Romania

Anthos Investigative Site 9001; 🇷🇴 Brăila, Romania

Anthos Investigative Site 9023; 🇷🇴 Bucharest, Romania

Anthos Investigative Site 9019; 🇷🇴 Bucuresti, Romania

Anthos Investigative Site 9024; 🇷🇴 Cluj-Napoca, Romania

Anthos Investigative Site 9017; 🇷🇴 Craiova, Romania

Anthos Investigative Site 9006; 🇷🇴 Craiova, Romania

Anthos Investigative Site 9010; 🇷🇴 Oradea, Romania

Anthos Investigative Site 9025; 🇷🇴 Piteşti, Romania

Anthos Investigative Site 9014; 🇷🇴 Piteşti, Romania

Anthos Investigative Site 9012; 🇷🇴 Satu Mare, Romania

Anthos Investigative Site 9007; 🇷🇴 Timişoara, Romania

Anthos Investigative Site 9005; 🇷🇴 Timişoara, Romania

Anthos Investigative Site 9018; 🇷🇴 Timişoara, Romania

Anthos Investigative Site 9013; 🇷🇴 Timişoara, Romania

Anthos Investigative Site 9008; 🇷🇴 Timişoara, Romania

Anthos Investigative Site 9003; 🇷🇴 Târgu-Mureş, Romania

Anthos Investigative Site 9004; 🇷🇴 Târgu-Mureş, Romania

Anthos Investigative Site 9016; 🇷🇴 Târgu-Mureş, Romania

Anthos Investigative Site 9021; 🇷🇴 Târgu-Mureş, Romania

Anthos Investigative Site 2411; 🇿🇦 Bellville, South Africa

Anthos Investigative Site 2409; 🇿🇦 Benoni, South Africa

Anthos Investigative Site 2417; 🇿🇦 Cape Town, South Africa

Anthos Investigative Site 2408; 🇿🇦 Centurion, South Africa

Anthos Investigative Site 2412; 🇿🇦 Durban, South Africa

Anthos Investigative Site 2416; 🇿🇦 Johannesburg, South Africa

Anthos Investigative Site 2402; 🇿🇦 Pretoria, South Africa

Anthos Investigative Site 2414; 🇿🇦 Pretoria, South Africa

Anthos Investigative Site 2415; 🇿🇦 Somerset West, South Africa

Anthos Investigative Site 2405; 🇿🇦 Tongaat, South Africa

Anthos Investigative Site 1108; 🇪🇸 A Coruña, Spain

Anthos Investigative Site 1116; 🇪🇸 Almería, Spain

Anthos Investigative Site 1121; 🇪🇸 Barcelona, Spain

Anthos Investigative Site 1120; 🇪🇸 Barcelona, Spain

Anthos Investigative Site 1109; 🇪🇸 Cabra, Spain

Anthos Investigative Site 1103; 🇪🇸 Granada, Spain

Anthos Investigative Site 1111; 🇪🇸 Jaén, Spain

Anthos Investigative Site 1118; 🇪🇸 León, Spain

Anthos Investigative Site 1104; 🇪🇸 Madrid, Spain

Anthos Investigative Site 1117; 🇪🇸 Madrid, Spain

Anthos Investigative Site 1106; 🇪🇸 Madrid, Spain

Anthos Investigative Site 1113; 🇪🇸 Madrid, Spain

Anthos Investigative Site 1110; 🇪🇸 Murcia, Spain

Anthos Investigative Site 1105; 🇪🇸 Málaga, Spain

Anthos Investigative Site 1115; 🇪🇸 Oviedo, Spain

Anthos Investigative Site 1123; 🇪🇸 Sabadell, Spain

Anthos Investigative Site 1107; 🇪🇸 Santiago De Compostela, Spain

Anthos Investigative Site 1102; 🇪🇸 Sevilla, Spain

Anthos Investigative Site 1122; 🇪🇸 Sevilla, Spain

Anthos Investigative Site 1112; 🇪🇸 Terrassa, Spain

Anthos Investigative Site 1101; 🇪🇸 Valencia, Spain

Anthos Investigative Site 1119; 🇪🇸 Vigo, Spain

Anthos Investigative Site 1303; 🇬🇧 Corby, United Kingdom

Anthos Investigative Site 1313; 🇬🇧 Glasgow, United Kingdom

Anthos Investigative Site 1315; 🇬🇧 Hayle, United Kingdom

Anthos Investigative Site 1311; 🇬🇧 High Wycombe, United Kingdom

Anthos Investigative Site 1301; 🇬🇧 Isleworth, United Kingdom

Anthos Investigative Site 1316; 🇬🇧 King's Lynn, United Kingdom

Anthos Investigative Site 1309; 🇬🇧 Leeds, United Kingdom

Anthos Investigative Site 1314; 🇬🇧 London, United Kingdom

Anthos Investigative Site 1319; 🇬🇧 London, United Kingdom

Anthos Investigative Site 1308; 🇬🇧 London, United Kingdom

Anthos Investigative Site 1312; 🇬🇧 Manchester, United Kingdom

Anthos Investigative Site 1307; 🇬🇧 Newcastle Upon Tyne, United Kingdom

Anthos Investigative Site 1318; 🇬🇧 Norwich, United Kingdom

Anthos Investigative Site 1305; 🇬🇧 Peterborough, United Kingdom

Anthos Investigative Site 1302; 🇬🇧 Stevenage, United Kingdom

Anthos Investigative Site 1310; 🇬🇧 Stockton-on-Tees, United Kingdom

Anthos Investigative Site 1317; 🇬🇧 Stoke-on-Trent, United Kingdom

Anthos Investigative Site 1306; 🇬🇧 Taunton, United Kingdom