Pressure controlled ventilation with 5 vs 10 cm H2O in children undergoing laparoscopic surgery under general anaesthesia
Not Applicable
Completed
- Conditions
- Health Condition 1: K35- Acute appendicitisHealth Condition 2: null- children aged 2 to 10 years undergoing laparoscopic surgeryHealth Condition 3: K80- CholelithiasisHealth Condition 4: K40- Inguinal herniaHealth Condition 5: N13- Obstructive and reflux uropathyHealth Condition 6: Q53- Undescended and ectopic testicle
- Registration Number
- CTRI/2017/11/010592
- Lead Sponsor
- Department of Anaesthesia Intensive Care PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
children of age 2 to 10 years and ASA physical status I or II undergoing laparoscopic procedures under general anaesthesia.
Exclusion Criteria
Children with predicted difficult intubation and ventilation
Acute respiratory tract infection
Severe/active cardiopulmonary disease
Previous H/O or family H/O malignant hyperthermia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Compare and assess the effect of 5 & 10 cm H2O PEEP on oxygenation in children undergoing laparoscopic procedures under GA <br/ ><br> <br/ ><br>Timepoint: T1: Baseline value with the patient in the supine position 2 minutes after tracheal intubation and stabilization on the ventilator. <br/ ><br>T2: 2 minutes after insufflating CO2 to an intra-abdominal pressure of 12 mmHg. <br/ ><br>T3: 1 hour After applying PEEP 5 or 10cm H20. <br/ ><br>T4: After completing the surgical procedure with the patient returned to the supine position with the abdomen deflated
- Secondary Outcome Measures
Name Time Method Compare and assess the effect of 5 & 10 cm H2O PEEP on ventilation and hemodynamicparameters in children undergoing laparoscopic procedures under GA <br/ ><br>Timepoint: T1: Baseline value with the patient in the supine position 2 minutes after tracheal intubation and stabilization on the ventilator. <br/ ><br>T2: 2 minutes after insufflating CO2 to an intra-abdominal pressure of 12 mmHg. <br/ ><br>T3: 1 hour After applying PEEP 5 or 10cm H20. <br/ ><br>T4: After completing the surgical procedure with the patient returned to the supine position with the abdomen deflated <br/ ><br>