Electroretinographic finding in adult Thalassemia patients with long-term use of iron chelating agents at Siriraj hospital

Recruiting

• Conditions: iron chelating; Electroretinographic finding in adult Thalassemia patients with long-term use of iron chelating agents at Siriraj hospital; Thalassemia; Electroretinographic

• Registration Number: TCTR20221130003
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-30
• Study Completion: 2023-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Age > 18 years
2. Patients with thalassemia who have taken iron chelating more than 15 years

Exclusion Criteria

1. Patient has history of ophthalmic disease or eye abnormality before. such as Cataract, Glaucoma, Optic neuropathy, Maculopathy etc.
2. Patients have eye surgery or accident before.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Electroretinographic finding in adult Thalassemia patients with long-term use of iron chelating agents first visit Change in amplitude and implicit time of electroretinography in adult thalassemia patients who received iron chelating agents

Secondary Outcome Measures

Name	Time	Method
Eye abnormality first visit Visual acuity, Color test, Visual field test, Retina change