Clinical Trial on Dry Eyes
- Conditions
- Health Condition 1: H041- Other disorders of lacrimal gland
- Registration Number
- CTRI/2024/01/061897
- Lead Sponsor
- V Prasad Eye Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Aged 18–70 years
2. Have OSDI scores =33 or Oxford staining grade =2
3. Have a best corrected visual acuity (BCVA) in both eyes of +0.7 logMAR
4.Diagnosis of DED in both eyes supported by the criteria mentioned below
Defined by at least one eye meeting all the following criteria:
o A symptom severity score of =22 for OSDI
oAn unanesthetized Schirmer Tear Test (STT) score of =1 mm and =5 mm per 5 minutes
oEvidence of ocular surface staining (total fluorescein staining score of at least 3) [0-15 scale])
5. Have normal lid anatomy and no other ocular disease except refractive errors or cataract
1. Uncontrolled systemic diseases, active infection or chronic kidney disease, liver cirrhosis, advance cancer.
2. Pregnant or nursing women.
3.Have not recently used the following medications, interventions, surgery, Anticoagulants or anti-platelets,Topical undiluted blood products within 3 months, Punctal plug or contact lenses, Ocular surgery within 6 months.
4.Have no contraindication for blood donation, Positive HIV, hepatitis B or C, or syphilis, Anaemia.Hemoglobin less than 110 grams per Litre.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method