Quantitative Electroencephalography as a predictor of treatment Response to Divalproex sodium versus Lithium in Bipolar affective disorder

Department of psychiatry Government medical college and hospital sector Chandigarh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Patient or nominated representative willing for consent
•2.Patients in the age group 18-45
•3.Patients currently not on treatment with lithium or divalproex sodium, though might have received the same in the past (upto 2 weeks prior to the assessment)
•4.Patients with YMRS score >12 & HAM-D <7 on initial assessment
•5.Patients diagnosed with Bipolar affective disorder with current episode mania or hypomania as per DSM 5 criteria

•1.Patients diagnosed with bipolar affective disorder current episode depressive with psychosis or current episode with psychosis of YMRS > 12 & HAM-D > 7
•2.Patient on any Psychotropic drugs in the past 2 weeks
•3.Patient on any other therapy (pharmacological, psychotherapy or somatic therapy) in the current episode
•4.Patients diagnosed with other unstable medical (Hypothyroidism, Diabetes inscipidus, Myasthenia gravis, Chronic heart disease, Kidney disease, Hepatic failure, Pancreatitis, Bleeding disorders), neurological (Hyperammonemic encephalopathy, epilepsy) or surgical disorders
•5.Patients who were unresponsive to either lithium or divalproex sodium in the past episodes
•6.Patients who have received ECT in past 3 months
•7.History of intolerance to either lithium or divalproex sodium because of the side effects in the past episodes
•8.Pregnant or Breastfeeding Females
•9.Substance dependence (except nicotine/ caffeine) in past six months

发起方

Department of psychiatry Government medical college and hospital sector Chandigarh