Detecting bleeding problems in patients who develop very high BP during Pregnancy
Not Applicable
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2021/06/034324
- Lead Sponsor
- KMC Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
For Cases - Singleton pregnancy with Severe Pre-eclampsia requiring immediate intervention
Controls - Singleton pregnancy with Pre-eclampsia that can undergo expectant
management
Exclusion Criteria
For Cases - Pre-eclampsia patients that can undergo expectant management, Multiple gestation, Any other causes of bleeding in pregnancy
For Controls - Multiple gestation, Any other causes of bleeding in pregnancy, Patients with severe pre eclampsia and eclampsia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identification of type of coagulopathy based on scores of R value, K value, â??aâ?? angle, MA, CI, Ly30 <br/ ><br>â?¢ R value - Represents period of time of latency from start of test to initial fibrin formation <br/ ><br>â?¢ K time - Represents time taken to achieve a certain level of clot strength - equates to amplitude 20 mm <br/ ><br>â?¢ Alpha Angle Measures the rapidity of fibrin build-up and cross-linking (clot strengthening) <br/ ><br>â?¢ MA - represents the ultimate strength of the fibrin clot <br/ ><br>Timepoint: 4 months
- Secondary Outcome Measures
Name Time Method Providing Blood component as per result of TEG <br/ ><br>Further management as per protocol of hospital in high dependency unit.Timepoint: Outcome assessed every 8 weeks