Zoledronic acid, an osteoporosis drug, in chronic low back pain with specific findings on magnetic resonance imaging: a randomized controlled trial
Phase 1
Active, not recruiting
- Conditions
- Chronic low back painTherapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]MedDRA version: 18.1Level: LLTClassification code 10024891Term: Low back painSystem Organ Class: 100000004859
- Registration Number
- EUCTR2015-000751-25-FI
- Lead Sponsor
- Jaro Karppinen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
Low back pain lasting at least 3 months
Disabling low back pain (intensity at least 6 on a 0-10 scale or disability on Oswestry Disability Index at least 30%)
An inflammatory Modic change on MRI
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 250
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Red flags, recents spine surgery, severe renal impairment
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method