To compare respiratory muscle strength recovery using ultrasound after neuromuscular reversal with Neostigmine versus Sugammadex.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/01/061766
- Lead Sponsor
- Maulana Azad Medical College and associated Lok Nayak Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients 18 to 65 years of age
2.Patients having ASA physical status I and II
3.BMI < 30 Kg/m2
Exclusion Criteria
1.Pregnant or breastfeeding women
2.Patient with history of allergy to Sugammadex, Neostigmine or Vecuronium
3.Patient with renal or hepatic impairment
4.Patient with known neuromuscular disease
5.Suspected difficult airway
6.Patients in whom satisfactory ultrasound imaging or space for placement of the ultrasonic probe will be difficult
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Mean change in TFIO from baseline to 5 minutes post extubationTimepoint: At the time of induction & 5 minutes & 30 minutes after extubation
- Secondary Outcome Measures
Name Time Method 1. Mean change in thickness fraction of internal oblique from baseline to 30 minutes post extubation. <br/ ><br>2. Mean change in diaphragmatic thickness fraction from baseline to 5 and 30 minutes post extubation <br/ ><br>3. Mean time to train of four ratio recovery to 0.9Timepoint: From baseline to 30 minutes and from baseline to 5 and 30 minutes post extubation.