Statins and ARBs on Rheumatoid Activity

Phase 3

Recruiting

• Conditions: Rheumatoid Arthritis
• Interventions: Drug: Statins; Drug: Angiotensin receptor blockers

• Registration Number: NCT03770702
• Lead Sponsor: Sherief Abd-Elsalam

Brief Summary

Investigational and comparative study between the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Detailed Description

The study aims at ivestigating and comparing the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Study Timeline

• Study Start: 2018-10-01
• Status Verified: 2018-12
• Study First Submitted: 2018-12-07
• Study First Submitted QC: 2018-12-07
• Last Update Submitted: 2018-12-07
• Study First Posted: 2018-12-10
• Last Update Posted: 2018-12-10
• Primary Completion: 2025-12-01
• Study Completion: 2026-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Rheumatoid arthritis.

Exclusion Criteria

• Pregnant or lactating
• Hepatic or renal impairment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Statins	Statins	Statin + Traditional therapy.
Angiotensin receptor blockers	Angiotensin receptor blockers	ARB ( Angiotensin receptor blockers) + Traditional therpy.

Primary Outcome Measures

Name	Time	Method
Change in disease activity score	6 months	DAS28-ESR

Trial Locations

Locations (1)

Sherief Abd-Elsalam; 🇪🇬 Tanta, Egypt