Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section

Recruiting

• Conditions: Post Spinal Hypotension
• Interventions: Other: perfusion index in all parturient recruited for the study

• Registration Number: NCT05587153
• Lead Sponsor: Zagazig University

Brief Summary

Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section

Detailed Description

Hypotension following spinal anaesthesia may cause maternal dizziness, nausea, vomiting and fetal acidosis, administration of prophylactic vasopressor agents in pregnant women may cause undesirable effects on the mother and fetus. Perfusion index is the ratio of a pulsatile to a non-pulsatile fraction of blood volume. The increase of the pulsatile fraction manifested during vasodilatation corresponds to a higher PI. So, the patients with a higher PI have a higher risk for post-spinal hypotension. Elevated sympathetic activity before neuraxial anaesthesia was associated with a higher risk for post-spinal hypotension. The significant variability in haemodynamic after the positional change indicates higher sympathetic activity. The high the rise in autonomic activity, the higher the risk for post-spinal hypotension

AIM OF THE WORK:

Prediction of hypotension after spinal anaesthesia in caesarean section either by perfusion index and positional haemodynamic changes

Grouping:

All the recruited patients will be assessed by perfusion index. and by positional haemodynamic changes

Study Timeline

• Study First Submitted: 2022-03-08
• Study Start: 2022-07-15
• Study First Submitted QC: 2022-10-16
• Study First Posted: 2022-10-19
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-20
• Last Update Posted: 2022-12-23
• Primary Completion: 2022-12-30
• Study Completion: 2022-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Observational study in parturient who will be recruited for the study	perfusion index in all parturient recruited for the study	this study will include the eligible parturient who will be assessed by perfusion index and by positional hemodynamic changes.

Primary Outcome Measures

Name	Time	Method
Prediction of post-spinal hypotension using PI	6 months	To correlate between perfusion index and hypotension after spinal anaesthesia in caesarean section

Secondary Outcome Measures

Name	Time	Method
Prediction of post-spinal hypotension using positional hemodynamic changes	6 months	To correlate between positional haemodynamic changes and hypotension after spinal anaesthesia in caesarean section

Trial Locations

Locations (2)

Faculty of medicine; 🇪🇬 Zagazig, Egypt

Ramy; 🇪🇬 Zagazig, Egypt