Fasted High-Intensity Interval and Moderate-Intensity Continuous Exercise Are Not Associated With A Detrimental 24-Hour Blood Glucose Profile
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 2
- 主要终点
- 24 hour glycaemic profile
研究概览
简要总结
This study aims to compare the effect of a bout of high-intensity interval training (HIT) with a bout of moderate-intensity continuous training (MICT) on glucose concentrations over the subsequent 24h period.
详细描述
This study aims to compare the effect of a bout of high-intensity interval training (HIT) with a bout of moderate-intensity continuous training (MICT) on glucose concentrations over the subsequent 24h period. Fourteen people with type 1 diabetes (duration of type 1 diabetes 8.2±1.4 years), all on basal-bolus regimen, completed a randomised, counterbalanced, crossover study. Continuous glucose monitoring was used to assess glycaemic control following a single bout of HIT (6 x 1min intervals) and 30 mins of moderate-intensity continuous training (MICT) on separate days, compared to a non-exercise control day (CON). Exercise was undertaken following an overnight fast with omission of short-acting insulin. Capillary blood glucose samples were recorded pre and post-exercise to assess the acute changes in glycaemia during HIT and MICT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •duration of type 1 diabetes >6 months
- •basal bolus regimen
- •no significant history of hyper- or hypoglycaemia (determined from medical history
排除标准
- •duration of type 1 diabetes <6 months,
- •insulin pump therapy
- •significant history of hyper- or hypoglycaemia (determined from medical history)
- •obesity (BMI >30 kg∙m-2)
- •pregnancy or planning pregnancy, uncontrolled hypertension (>180/100 mmHg)
- •autonomic neuropathy
- •taking any medication that affects heart rate
- •major surgery planned within 6 weeks of the study
- •severe nonproliferative and
- •unstable proliferative retinopathy
研究组 & 干预措施
Control day with no exercise
glycaemic profile will be assessed using continuous glucose monitors following a single 24-hour period in which participants performed no exercise
干预措施: Effects of the type of exercise on blood glucose concentrations (Behavioral)
High intensity interval training (HIT)
glycaemic profile will be assessed using continuous glucose monitors following a 24-hour period whereby participants performed a single bout of high-intensity interval training (HIT) in the morning under fasted conditions
干预措施: Effects of the type of exercise on blood glucose concentrations (Behavioral)
moderate intensity continuous training (MICT)
glycaemic profile will be assessed using continuous glucose monitors following a 24-hour period whereby participants performed a single bout of moderate-intensity continuous training (MICT) in the morning under fasted conditions
干预措施: Effects of the type of exercise on blood glucose concentrations (Behavioral)
结局指标
主要结局
24 hour glycaemic profile
时间窗: 24 hours
Continuous glucose monitoring will be used to assess the effects of an acute bout of fasted high intensity interval training or moderate intensity continuous training on 24 hour glycaemic profile.
次要结局
未报告次要终点
研究者
Sam Shepherd
Lecturer/Senior Lecturer, Principle Investigator
Liverpool John Moores University