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Effectiveness of combined a cognitive training exercise with non-pharmacologic interventions to prevent and reduce severity of delirium in critically ill surgical patients

Phase 1
Conditions
Critically ill surgical patients
cognitive training exercises, non-pharmacological, older, surgical patient, intensive care unit
Registration Number
TCTR20230619002
Lead Sponsor
Faculty of Medicine Siriraj Hospital, Mahidol University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
164
Inclusion Criteria

1. Age of 65 years old or more
2.Patients undergoing surgery: general, cardiovascular and thoracic, vascular, urological, head and neck, orthopedic, gynecologic and obstetric
3. Anticipated LOS in SICU of more than 24 hours
4. A Richmond Agitation-Sedation Scale (RASS) score from -2 to +1
5. Hemodynamic stable: Systolic blood pressure (SBP) 90 to 180 mmHg, heart rate (HR) 60 to120 beats/min, the dose of norepinephrine less than 0.1 mcg/kg/min, and dopamine/dobutamine less than 5 mcg/kg/min
6. Respiratory system stability: positive end-expiratory pressure (PEEP) less than 10 cmH2O, and SpO2 more than 95%

Exclusion Criteria

1. Patients who cannot communicate in the Thai language
2. Serious receptive aphasia or severe visual or auditory impairment that precludes communication
3. Severe cognitive impairment or who have a MOCA score of less than 10
4. Severe mental disability
5. Patients who have delirium on admission

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
feasibility of using Thai cognitive training exercises After 7 consecutive days in the ICU and Ward or untill hospital discharge Practicability and burden scores,incidence of delirium Daily assessment of delirium after SICU admission or until hospital discharge or death CAM-ICU and Nu-DESC test
Secondary Outcome Measures
NameTimeMethod
duration of delirium Daily assessment of delirium after SICU admission or until hospital discharge or death CAM-ICU and Nu-DESC test,incidence of POCD Preoperative assessment and postoperative day 5 MOCA test,quality of life at hospital discharges EQ-5D-5
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