Repairing experimental tooth root perforations with different commercial materials
Completed
- Conditions
- Root perforationOral Health
- Registration Number
- ISRCTN17574766
- Lead Sponsor
- Clinica Odontoiatrica Salzano Tirone
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
1. Adults aged 18-60 years old
2. Healthy patients
3. Needing all-on-4 rehabilitation
4. Having at least two vital and periodontally healthy monoradicular teeth scheduled for extraction
Exclusion Criteria
1. Clinically significant medical history
2. Treated with immunosuppressive therapy or immunocompromised
3. Undergoing radiotherapy in the head/neck area
4. Previously treated or under treatment with intravenous amino-bisphosphonates
5. Pregnant or breastfeeding
6. Refusing to be included in the research protocol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Formation of mineralised tissue over the filling material material is measured using the histological analysis at 3 months <br>2. PDL fibres orientation is evaluated using thehistological analysis under polarised light at 3 months<br>3. Presence of inflammatory cell infiltrate, classified as follows: null, when there are no inflammatory cells; mild, when there are few inflammatory cells; moderate, when inflammatory cells do not replace the normal tissue; severe, when inflammatory cells replace the normal tissue is measured using the histological analysis at 3 months
- Secondary Outcome Measures
Name Time Method 1. The presence or absence of a fibrous capsule formation is measured using histological analysis at 3 months<br>2. Root resorption is measured using histological analysis at 3 months<br>3. Ankylosis is measured using histological analysis at 3 months<br>4. Epithelial proliferation is measured using histological analysis at 3 months<br>