Effect of Yeast protein compared to whey protein and a placebo on muscle mass and performance in an Adult Population – A double blind, randomised controlled trial.

Not Applicable

Completed

• Conditions: Muscle mass; Muscle performance; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12621000212853
• Lead Sponsor: RDC Global Pty Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-03
• Study Completion: 2022-08-20
• Last Update Posted: 27 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 127

Inclusion Criteria

•Male aged over 40 years old
•BMI 20.0-34.9
•Able to provide informed consent
•Undertaking low impact cardiovascular exercise including but not limited to cycling, swimming and walking not more than 5 x weekly
•Agree not to take other supplements (including protein or testosterone containing supplements) or medications (e.g. steroids) aimed at muscle mass growth for the duration of the trial.

Exclusion Criteria

•Currently undertaking resistance training exercise more than once a week
•Unstable or serious illness/impairment (e.g. kidney, liver, GIT, heart conditions, diabetes, thyroid gland function, Malignancy, lung conditions, chronic asthma, cognitive damage, mood disorders or neurological disorders such as MS)*
•Acute sickness experienced in the past 2 months
•Active smokers and/or nicotine or drug abuse
•Chronic alcohol use (>14 alcoholic drinks week)
•Allergic to any of the ingredients in active or placebo formula (e.g. milk, whey or yeast allergy)
•Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion
•Participants who have participated in any other exercise based clinical study during the past 3 month
•People who have or have had treatment for cancer, HIV or use of anabolic steroids in the past year.
•History of orthopedic injuries or surgery in the past 6 months

*An unstable illness is any illness that is currently not being treated with a stable dose of medication or is fluctuating in severity. A serious illness is a condition that carries a risk of mortality, negatively impacts quality of life and daily function and/or is burdensome in symptoms and/or treatments.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in lean muscle mass as measured by dual energy x-ray absorptiometry [Baseline, week 8 post-intervention commencement ]