Imaging-based evaluation of the treatment of tremor by targeted lesioning of the brai
- Conditions
- ThalamotomylesioningtremorDTI
- Registration Number
- NL-OMON21836
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 19
Inclusion Criteria
Adult patients (>18 years old)
- Treatment for tremor with (sub)thalamotomy in the UMCG
Exclusion Criteria
- Contra-indications to MRI examination (e.g. heart pacemaker, metal foreign body in eye, aneurysm clip in brain, severe claustrophobia)
- Implantation of DBS electrodes
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In all patients: relation between tremor severity and localization of the lesion. Relation between clinical tremor severity and radiographic (DTI) features of the cerebello-rubro-thalamic tract.<br /><br /><br><br>- The difference in localization of the lesioned area in the brain towards the preoperative assessed target measured in millimetres<br /><br>- The volume of the cerebello-rubro-thalamic tract involved in the lesioned area and compared to the contralateral side<br /><br>- Tremor severity as measured by accelerometers (amplitude and frequency) and the Bain & Findley Clinical Tremor Rating Scale
- Secondary Outcome Measures
Name Time Method Patient satisfaction after (sub)thalamotomy using a short questionnaire (VAS score).