High versus low blood pressure target strategy in geriatric patients with septic shock; a multicenter randomized controlled trial - High versus low blood pressure target strategy in geriatric patients with septic shock;

Japanese Association for Acute Medicine0 sites836 target enrollmentOctober 1, 2020

Overview

No summary available.

Registry

who.int

Start Date

October 1, 2020

End Date

March 13, 2024

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Japanese Association for Acute Medicine

•1\. Patients who are highly likely to be transferred to another hospital within 72 h of randomisation 2\. Patients who have been on vasopressors for 3 or more hours 3\. Patients experiencing cardiac arrest before randomisation 4\. Patients who are diagnosed with coronavirus disease 2019 5\. Patients who have the advanced directives restricting implementation of the standard critical care (e.g., catecholamine use, mechanical ventilation, and renal replacement therapy) 6\. Patients with other diseases that require stricter blood pressure control than for maintaining haemodynamics in septic shock (uncontrollable active bleeding, aneurysms, arterial dissection, etc.) 7\. Patients participating in other clinical trials that involve interventions 8\. Patients who need to be arrested, detained, or put in custody by law enforcement or legal agencies 9\. Patients who refuse to participate in the trial 10\. Patients deemed ineligible to participate by a clinical physician.