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Affective startle modulation in personality disordered offenders

Recruiting
Conditions
psychopathy
10034726
Registration Number
NL-OMON30963
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

Psychopathy (pcl-r score >=26)
Antisocial personality disorder according to the DSM-IV criteria

Exclusion Criteria

Specific exclusion criteria for patients: psychotic patients.
Exclusion criteria for both patients and controls: colour blindness, deafness or hard of hearing, neurological, cardiovascular, and respiratory diseases. Subjects will also be excluded when they cannot understand the Dutch language sufficiently to understand the purposes and implications of the experiment.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Emotional functioning of psychopaths and ASPD-patients with a low PCL-R score<br /><br>will be studied by means of psychophysiological (Heart rate, blood pressure,<br /><br>skin conductance, breathing rate and eyeblink and post-auricular EMG), HPA axis<br /><br>(Salivary cortisol levels) and psychodiagnostic and risk-assessment instruments<br /><br>to investigate whether there are subgroups of antisocial offenders, who can be<br /><br>differentiated on the basis of affective response patterns. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Type and dose of medication<br /><br>Duration of treatment with medication<br /><br>Criminological anamnesis<br /><br>Type and number of convictions<br /><br>Age of first conviction</p><br>
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