Relationship of MTHFR gene and schizophrenia
- Conditions
- Health Condition 1: G- Mental Health
- Registration Number
- CTRI/2020/08/027329
- Lead Sponsor
- Government Medical College and Hospital Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1) Patients diagnosed with schizophrenia as per ICD 11
2) Age of the patients shall be between 18-45 years.
3) Patients not on any psychotropics for past 2 weeks.
4) Patients willing to participate and give consent or in case the patient lacks mental capacity, his/her nominated representative willing to give consent to participate.
5) Patients not having a major diet change that is shifting of non vegetarian diet to vegetarian diet or vice versa in past 3 months.
1) Patients who are not willing to give consent.
2) Pregnant and breast feeding patients.
3) Patients with co-morbid psychiatric illness and substance dependence.
4) Patients with severe medical and surgical illness.
5) Patients with history of depot antipsychotic administration in the past 3 months.
6) Patient already on vitamin b12 and folic acid supplements.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to compare the improvement in psychopathology in patients with first episode schizophrenia receiving risperidone alone and risperidone plus vitamin B12 and folic acid supplements at 6 weeks respectivelyTimepoint: baseline, 2 weeks,4 weeks, 6 weeks
- Secondary Outcome Measures
Name Time Method To compare the improvement in psychopathology in patients with first episode Schizophrenia receiving Risperidone alone and Risperidone plus Vitamin B12 and Folic acid supplements at 6 weeks respectivelyTimepoint: 6 weeks