An exploratory study of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism frequencies in men and women of reproductive age
Not Applicable
- Conditions
- Reproductive age Men and women suspected of infertility
- Registration Number
- JPRN-UMIN000053294
- Lead Sponsor
- Kameda IVF Clinic Makuhari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
Not provided
Exclusion Criteria
Those deemed ineligible at the discretion of the principal investigator
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method genotype frequencies of the following MTHFR genotypes in men and women of reproductive age
- Secondary Outcome Measures
Name Time Method Male: Semen analysis (semen volume, sperm concentration, motility), semen oxidation-reduction potential (sORP test), sperm DNA fragmentation index test (sperm DFI test) History of urological diseases and surgeries at the time of interview, sexual desire and sexual intercourse, SHIM diagnostic test results, etc. Measurement of serum folate and homocysteine Women Menstrual estrogen, progesterone, LH, FSH, PRL, AMH, etc. Results of questionnaires on menstruation, pregnancy, medications/medical history, surgical history, infertility treatment history, etc. at the time of interview Serum folate and homocysteine levels