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Cardiac Stroke Volume at Rest and During Different Exercise Intensities

Not Applicable
Conditions
Cardiac Function
Interventions
Behavioral: Acute exercise
Registration Number
NCT04287114
Lead Sponsor
Turku University Hospital
Brief Summary

The main aim of the present investigation is to study cardiac function in different exercise intensities in healthy human subjects. Two techniques will be used: cardiac ultrasound-derived stroke volume measurements and body impedance measurements. 20 healthy men (n=10) and women (n=10) aged 18-45 years will be investigated at rest and during exercise. All study procedures are non-invasive.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Age 18-45
  • BMI 18-30
  • Resting Blood pressure < 140/90 mmHg
  • Participation in regular exercise
Exclusion Criteria
  • Acute illness
  • Pregnancy
  • Pace maker
  • Artificial joint
  • History of a cardiac event
  • Insulin or medically treated diabetes
  • Any chronic disease or condition that could create a hazard to the subject safety, endanger the study procedures or interfere with the interpretation of study results
  • Abundant use of alcohol
  • Use of narcotics
  • Smoking of tobacco or consuming snuff tobacco
  • Diagnosed depressive or bipolar disorder
  • Abnormalities in resting ECG (revised by the study physician)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Healthy young men and womenAcute exerciseSingle group consisting of 10 men and 10 women
Primary Outcome Measures
NameTimeMethod
Cardiac stroke volume1 min
Secondary Outcome Measures
NameTimeMethod
Ejection fraction1 min
End-diastolic and end-systolic volumes1 min

Trial Locations

Locations (2)

University of Turku

🇫🇮

Turku, Finland

Turku PET Centre

🇫🇮

Turku, Finland

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